Mohit Biglarian1, Morsal Momeni Larimi2, Hamid Hassanzadeh Afrouzi3, Abouzar Moshfegh3, Davood Toghraie4, Ashkan Javadzadegan5, Sara Rostami6. 1. Faculty of Mechanical Engineering, Sharif University of Technology, Tehran, Iran. 2. Faculty of Mechanical Engineering, Babol Noshirvani University of Technology, Babol, Iran. 3. ANZAC Research Institute, the University of Sydney, Sydney NSW 2139, Australia. 4. Department of Mechanical Engineering, Khomeinishahr Branch, Islamic Azad University, Khomeinishahr, Iran. 5. Faculty of Medicine and Health Sciences, Macquarie University, Sydney NSW 2109, Australia. 6. Laboratory of Magnetism and Magnetic Materials, Advanced Institute of Materials Science, Ton Duc Thang University, Ho Chi Minh City, Vietnam; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam. Electronic address: sara.rostami@tdtu.edu.vn.
Abstract
BACKGROUND AND OBJECTIVE: Blood flow variation during cardiac cycle is the main mechanism of atherosclerotic development which is dependent on. METHODS: The present work mainly tends to investigate stenosis effect in dynamic curvature of coronary artery. This paper presents numerical investigations on wall shear stress profiles in three-dimensional pulsatile flow through curved stenotic coronary arteries for both static and dynamic model. In order to do so, three-dimensional models related to the curved arteries with two degrees of stenosis (30% and 50%). RESULTS: Lower amount of wall shear stress is found near the inner wall of artery distal to the plaque region (stenosis) and in both percentages of stenosis the maximum wall shear stress will accrue in the middle of the stenosis; however it is much more in the higher rate of stenosis. CONCLUSIONS: A chaotic wall shear stress region is also observed downstream of stenosis in the severe stenosis case. Finally it concluded that the arterial wall motion affects the wall shear stress and the plaque formation site.
BACKGROUND AND OBJECTIVE: Blood flow variation during cardiac cycle is the main mechanism of atherosclerotic development which is dependent on. METHODS: The present work mainly tends to investigate stenosis effect in dynamic curvature of coronary artery. This paper presents numerical investigations on wall shear stress profiles in three-dimensional pulsatile flow through curved stenotic coronary arteries for both static and dynamic model. In order to do so, three-dimensional models related to the curved arteries with two degrees of stenosis (30% and 50%). RESULTS: Lower amount of wall shear stress is found near the inner wall of artery distal to the plaque region (stenosis) and in both percentages of stenosis the maximum wall shear stress will accrue in the middle of the stenosis; however it is much more in the higher rate of stenosis. CONCLUSIONS: A chaotic wall shear stress region is also observed downstream of stenosis in the severe stenosis case. Finally it concluded that the arterial wall motion affects the wall shear stress and the plaque formation site.