Grace A Masters1, Linda Brenckle2, Padma Sankaran3, Sharina D Person4, Jeroan Allison5, Tiffany A Moore Simas6, Jean Y Ko7, Cheryl L Robbins8, Wendy Marsh9, Nancy Byatt10. 1. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Grace.Masters@UMassMed.edu. 2. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Linda.Brenckle@UMassMed.edu. 3. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Padma.Sankaran@UMassMed.edu. 4. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Sharina.Person@UMassMed.edu. 5. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Jeroan.Allison@UMassMed.edu. 6. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: TiffanyA.MooreSimas@UMassMemorial.org. 7. Centers for Disease Control and Prevention, Atlanta, GA, United States of America; U.S. Public Health Service Commissioned Corps, Rockville, MD, United States of America. Electronic address: fob1@cdc.gov. 8. Centers for Disease Control and Prevention, Atlanta, GA, United States of America. Electronic address: ggf9@cdc.gov. 9. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: Wendy.Marsh@UmassMemorial.org. 10. University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: Nancy.Byatt@UMassMemorial.org.
Abstract
OBJECTIVE: Bipolar disorder affects 2-8% of pregnant and postpartum women; untreated illness is associated with poor outcomes. This study aimed to describe bipolar disorder screening rates in obstetric settings and associated characteristics. METHOD: Women were recruited during pregnancy through three months postpartum from 14 obstetric clinics in Massachusetts. The Mood Disorder Questionnaire (MDQ) was used to screen for bipolar disorder; a subset previously diagnosed with bipolar was also examined. Differences in characteristics by screening outcome were tested using chi-square and t-tests. RESULTS: Of 574 participating women, 18.8% screened positive for bipolar disorder. Compared to those with negative, those with positive bipolar screens had 18.5-times the prevalence of positive substance use screens (11.1% vs. 0.6%, p < 0.001) and 3.4-times reported feeling they were not receiving adequate psychiatric help (24.0 vs. 7.0%, p < 0.001). Less than half of those with positive bipolar screens (42.0%) and 61.3% with pre-existing bipolar reported receiving current psychiatric care. CONCLUSIONS: Almost one in five perinatal women screened positive for bipolar disorder. Positive screenings were associated with comorbid substance use and low treatment rates. This study highlights the importance of screening for bipolar disorder during the perinatal period and the need for systematic approaches to ensure adequate assessment and follow-up. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov identifier: NCT02760004.
OBJECTIVE:Bipolar disorder affects 2-8% of pregnant and postpartum women; untreated illness is associated with poor outcomes. This study aimed to describe bipolar disorder screening rates in obstetric settings and associated characteristics. METHOD:Women were recruited during pregnancy through three months postpartum from 14 obstetric clinics in Massachusetts. The Mood Disorder Questionnaire (MDQ) was used to screen for bipolar disorder; a subset previously diagnosed with bipolar was also examined. Differences in characteristics by screening outcome were tested using chi-square and t-tests. RESULTS: Of 574 participating women, 18.8% screened positive for bipolar disorder. Compared to those with negative, those with positive bipolar screens had 18.5-times the prevalence of positive substance use screens (11.1% vs. 0.6%, p < 0.001) and 3.4-times reported feeling they were not receiving adequate psychiatric help (24.0 vs. 7.0%, p < 0.001). Less than half of those with positive bipolar screens (42.0%) and 61.3% with pre-existing bipolar reported receiving current psychiatric care. CONCLUSIONS: Almost one in five perinatal women screened positive for bipolar disorder. Positive screenings were associated with comorbid substance use and low treatment rates. This study highlights the importance of screening for bipolar disorder during the perinatal period and the need for systematic approaches to ensure adequate assessment and follow-up. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov identifier: NCT02760004.
Authors: Emma Robertson Blackmore; David R Rubinow; Thomas G O'Connor; Xiang Liu; Wan Tang; Nick Craddock; Ian Jones Journal: Bipolar Disord Date: 2013-05-07 Impact factor: 6.744
Authors: Tiffany A Moore Simas; Linda Brenckle; Padma Sankaran; Grace A Masters; Sharina Person; Linda Weinreb; Jean Y Ko; Cheryl L Robbins; Jeroan Allison; Nancy Byatt Journal: BMC Pregnancy Childbirth Date: 2019-07-22 Impact factor: 3.007
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