Literature DB >> 31709455

Budget impact analysis of osteoporosis medications for primary prevention of fractures in Taiwan.

Kun-Ling Wu1,2, Chih-Hsing Wu3,4, Yin-Fan Chang3, Yun-Ting Lin5, Jason C Hsu6,7.   

Abstract

INTRODUCTION: Taiwan's national health insurance currently only covers the use of osteoporosis drugs for the secondary prevention of fractures and does not provide coverage for primary prevention. The purpose of this study is to develop a model for analyzing the budgetary impact of the use of osteoporosis medications of primary prevention.
METHODS: The budget impact model in this study is the "actual medication cost" minus the "medical expenses for all types of fractures that can be avoided by taking osteoporosis medications." We developed six possible insurance payment plans for primary prevention based on the age of the patients and T-scores and performed eleven steps to estimate the budget impact of each payment plan.
RESULTS: The results of this study indicated that there may be 71,220 (T-score ≤ - 3.0, 75 + y/o) to 157,515 (T-score ≤ - 2.5, 65 + y/o) people using the drugs, and the budget impact may be US$26.28-58.98 million in 2019. However, the payment plans may avoid 492-766 fracture events and save medical expenditures for fracture treatment by US$1.30-2.02 million. The average costs for primary prevention within a year will be US$53,386-77,006.
CONCLUSION: The budget impact of using osteoporosis medications to primary prevention of fractures is significant, but it can be compensated due to savings in fracture treatment costs.

Entities:  

Keywords:  Budget impact analysis; Osteoporosis medication; Primary prevention; Taiwan

Mesh:

Year:  2019        PMID: 31709455     DOI: 10.1007/s00774-019-01061-5

Source DB:  PubMed          Journal:  J Bone Miner Metab        ISSN: 0914-8779            Impact factor:   2.626


  23 in total

1.  Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group.

Authors:  D M Black; D E Thompson; D C Bauer; K Ensrud; T Musliner; M C Hochberg; M C Nevitt; S Suryawanshi; S R Cummings
Journal:  J Clin Endocrinol Metab       Date:  2000-11       Impact factor: 5.958

2.  Estimated prevalence of orthopaedic fractures in Taiwan--A cross-sectional study based on nationwide insurance data.

Authors:  Nan-Ping Yang; Chien-Lung Chan; I-Liang Yu; Cheng-Yang Lee; Pesus Chou
Journal:  Injury       Date:  2010-06-17       Impact factor: 2.586

Review 3.  Guidelines for conducting pharmaceutical budget impact analyses for submission to public drug plans in Canada.

Authors:  Deborah A Marshall; Patrick R Douglas; Michael F Drummond; George W Torrance; Stuart Macleod; Orlando Manti; Lokanadha Cheruvu; Ron Corvari
Journal:  Pharmacoeconomics       Date:  2008       Impact factor: 4.981

4.  Octaplas compared with fresh frozen plasma to reduce the risk of transmitting lipid-enveloped viruses: an economic analysis and budget impact analysis.

Authors: 
Journal:  CADTH Technol Overv       Date:  2010-03-01

5.  Assessing the effect of Taiwan's outpatient prescription drug copayment policy in the elderly.

Authors:  Shuen-Zen Liu; James C Romeis
Journal:  Med Care       Date:  2003-12       Impact factor: 2.983

6.  Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific region.

Authors:  Chih-Hsing Wu; Eugene V McCloskey; Joon Kiong Lee; Akira Itabashi; Richard Prince; Wei Yu; Julie Li-Yu; Siok Bee Chionh; Yanling Zhao; Chan Soo Shin; Tirtarahardja Gunawan; Keh-Sung Tsai; Poon-Ung Chieng; Sheng-Pin Changlai; Ding-Cheng Chan; Jung-Fu Chen; S Bobo Tanner; Didier B Hans; John A Kanis; Yin-Fan Chang; Zih-Jie Sun; Rong-Sen Yang
Journal:  J Clin Densitom       Date:  2013-07-31       Impact factor: 2.617

7.  Denosumab for prevention of fractures in postmenopausal women with osteoporosis.

Authors:  Steven R Cummings; Javier San Martin; Michael R McClung; Ethel S Siris; Richard Eastell; Ian R Reid; Pierre Delmas; Holly B Zoog; Matt Austin; Andrea Wang; Stepan Kutilek; Silvano Adami; Jose Zanchetta; Cesar Libanati; Suresh Siddhanti; Claus Christiansen
Journal:  N Engl J Med       Date:  2009-08-11       Impact factor: 91.245

8.  Therapies for treatment of osteoporosis in US women: cost-effectiveness and budget impact considerations.

Authors:  Anna N A Tosteson; Russel T Burge; Deborah A Marshall; Robert Lindsay
Journal:  Am J Manag Care       Date:  2008-09       Impact factor: 2.229

Review 9.  A systematic review of hip fracture incidence and probability of fracture worldwide.

Authors:  J A Kanis; A Odén; E V McCloskey; H Johansson; D A Wahl; C Cooper
Journal:  Osteoporos Int       Date:  2012-03-15       Impact factor: 4.507

10.  Secular trends in incidence and recurrence rates of hip fracture: a nationwide population-based study.

Authors:  F-P Chen; Y-C Shyu; T-S Fu; C-C Sun; A-S Chao; T-L Tsai; T-S Huang
Journal:  Osteoporos Int       Date:  2016-11-10       Impact factor: 4.507

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  2 in total

1.  The association between osteoporosis medications and lowered all-cause mortality after hip or vertebral fracture in older and oldest-old adults: a nationwide population-based study.

Authors:  Chia-Chun Li; Jason C Hsu; Fu-Wen Liang; Yin-Fan Chang; Ching-Ju Chiu; Chih-Hsing Wu
Journal:  Aging (Albany NY)       Date:  2022-03-01       Impact factor: 5.682

2.  The economic burden of hip fractures in Asia.

Authors:  Ta-Wei Tai; Yu-Hsuan Lin; Chao-Jui Chang; Chih-Hsing Wu
Journal:  Osteoporos Sarcopenia       Date:  2021-06-16
  2 in total

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