| Literature DB >> 31708009 |
Tao Huang1, Wenjing Gao1, Jun Lv1, Canqing Yu1, Tao Wu1, Shengfeng Wang1, Chunxiao Liao1, Lu Meng1, Dongmeng Wang1, Zhaonian Wang1, Zengchang Pang2, Min Yu3, Hua Wang4, Xianping Wu5, Zhong Dong6, Fan Wu7, Guohong Jiang8, Xiaojie Wang9, Yu Liu10, Jian Deng11, Lin Lu12, Weihua Cao1, Liming Li1.
Abstract
The Chinese National Twin Registry (CNTR), initiated in 2001, has now become the largest twin registry in Asia. From 2015 to 2018, the CNTR continued to receive Chinese government funding and had recruited 61,566 twin-pairs by 2019 to study twins discordant for specific exposures such as environmental factors, and twins discordant for disease outcomes or measures of morbidity. Omic data, including genetics, genomics, metabolomics, and proteomics, and gut microbiome will be tested. The integration of omics and digital technologies in public health will advance our understanding of precision public health. This review introduces the updates of the CNTR, including study design, sample size, biobank, zygosity assessment, advances in research and future systems epidemiologic research.Entities:
Keywords: Omic data; precision public health; systems epidemiology; twin discordance; twins
Year: 2019 PMID： 31708009 DOI： 10.1017/thg.2019.85
Source DB: PubMed Journal: Twin Res Hum Genet ISSN： 1832-4274 Impact factor: 1.587