| Literature DB >> 31704038 |
Sukeshi Patel Arora1, Gabor Liposits2, Susan Caird3, Richard F Dunne4, Gordon Taylor Moffat5, David Okonji6, Maria Grazia Rodriquenz7, Divyanshu Dua8, Efrat Dotan9.
Abstract
Given the prevalence and the rising incidence of hepatocellular carcinoma (HCC) in older adults worldwide, there is an urgent need to improve our understanding of the implications of treatment modalities in this population. The care of older patients with HCC is challenging due to the lack of evidence-based recommendations in this population. The current treatment approach for older patients relies on extrapolation of data from clinical trials conducted mostly in younger patients or fit older adults. Further, in the last few years, the arsenal of systemic treatments has increased with currently seven FDA-approved therapies available for patients with advanced HCC. Therefore, understanding how to apply current data to this unique and diverse patient population is necessary. This review will aim to shed light on the approach to older adults with HCC through an assessment of available data in the literature.Entities:
Keywords: Geriatric assessment; Hepatocellular carcinoma; Multimodality treatment; Older adult
Mesh：
Year: 2019 PMID： 31704038 PMCID： PMC7188597 DOI： 10.1016/j.jgo.2019.10.007
Source DB: PubMed Journal: J Geriatr Oncol ISSN： 1879-4068 Impact factor: 3.599