Literature DB >> 31703767

From Mother or Father: Uniparental Embryos Uncover Parent-of-Origin Effects in Humans.

Eishi Aizawa1, Anton Wutz2.   

Abstract

In mammals, both parents make unique contributions to the offspring and maternal and paternal genomes are required for development. Two recent papers in Cell Stem Cell (Leng et al., 2019; Sagi et al., 2019) study uniparental embryos and uniparental embryonic stem cells to interrogate parent-of-origin effects in human embryogenesis.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31703767     DOI: 10.1016/j.stem.2019.10.007

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  1 in total

1.  Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation.

Authors:  Yanhe Li; Yuteng Weng; Dandan Bai; Yanping Jia; Yingdong Liu; Yalin Zhang; Xiaochen Kou; Yanhong Zhao; Jingling Ruan; Jiayu Chen; Jiqing Yin; Hong Wang; Xiaoming Teng; Zuolin Wang; Wenqiang Liu; Shaorong Gao
Journal:  Nat Commun       Date:  2020-09-14       Impact factor: 14.919

  1 in total

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