Literature DB >> 31703612

Osteomyelitis of the pubic symphysis caused by methicillin-resistant Staphylococcus aureus after vaginal delivery: a case report and literature review.

Stefano Cosma1, Fulvio Borella2, Andrea Carosso1, Agata Ingala3, Federica Fassio3, Tiziana Robba4, Aldo Maina5, Luca Bertero6, Chiara Benedetto1.   

Abstract

BACKGROUND: Osteomyelitis of the pubic symphysis is a rare cause of pelvic pain after delivery, mainly caused by Staphylococcus aureus and Pseudomonas aeruginosa. The clinical context is the same as the more common diastasis of the pubic bone, but the presence of intense local pain in association with fever should prompt further clinical work-up based on blood chemistry, microbiology and diagnostic imaging. We report the first case of methicillin-resistant Staphylococcus aureus osteomyelitis of the pubic symphysis occuring after the delivery. CASE
PRESENTATION: A 39-year-old woman developed pain over the pubic bone 12 h after the delivery. After 72 h fever rose and laboratory examination showed elevation of C-reactive protein and procalcitonin levels. Pelvic x-rays and magnetic resonance showed pubic diastasis, joint effusion, tiny irregularities of articular surfaces and, severe bone edema. The patient was started on broad spectrum intravenous (IV) antibiotics (piperacillin-tazobactam) and then replaced to IV vancomycin and oral levofloxacin based on antibiogram result. She was then discharged with oral antibiotic therapy and fully recovered.
CONCLUSIONS: Due to the rarity of this disease, we compared our experience with the other cases of osteomyelitis of pubic symphysis occurring in peri-postpartum reported in the literature. The course of osteomyelitis was favourable in all patients, and only in one case an additional orthopedic procedure for symphysis fixation was necessary. Knowledge of this rare condition is important to enable prompt diagnosis and treatment.

Entities:  

Keywords:  Osteomyelitis; Postpartum; Pregnancy; Pubic diastasis; Septic arthritis; Staphylococcus aureus

Mesh:

Substances:

Year:  2019        PMID: 31703612      PMCID: PMC6842141          DOI: 10.1186/s12879-019-4595-x

Source DB:  PubMed          Journal:  BMC Infect Dis        ISSN: 1471-2334            Impact factor:   3.090


  22 in total

1.  Osteomyelitis of the pubic symphysis - A case report.

Authors:  L Froberg; H Eckardt
Journal:  J Obstet Gynaecol       Date:  2015-06-02       Impact factor: 1.246

2.  Transmission of ST8-USA300 Latin American Variant Methicillin-Resistant Staphylococcus aureus on a Neonatal Intensive Care Unit: Recurrent Skin and Soft- Tissue Infections as a Marker for Epidemic Community-Associated-MRSA Colonization.

Authors:  Dennis Nurjadi; Sabrina Klein; Stefan Zimmermann; Klaus Heeg; Philipp Zanger
Journal:  Infect Control Hosp Epidemiol       Date:  2017-05-18       Impact factor: 3.254

3.  Osteomyelitis pubis occurring after spontaneous vaginal delivery: a case presentation.

Authors:  C Eskridge; S Longo; J Kwark; A Robichaux; W Begneaud
Journal:  J Perinatol       Date:  1997 Jul-Aug       Impact factor: 2.521

Review 4.  Osteitis or osteomyelitis of the pubis? A diagnostic and therapeutic challenge: report of 9 cases and review of the literature.

Authors:  Stefan Michael Knoeller; Markus Uhl; Georg Werner Herget
Journal:  Acta Orthop Belg       Date:  2006-10       Impact factor: 0.500

5.  MRI findings of septic arthritis and associated osteomyelitis in adults.

Authors:  Michael Karchevsky; Mark E Schweitzer; William B Morrison; J Antoni Parellada
Journal:  AJR Am J Roentgenol       Date:  2004-01       Impact factor: 3.959

Review 6.  The use of procalcitonin in the diagnosis of bone and joint infection: a systemic review and meta-analysis.

Authors:  C-J Shen; M-S Wu; K-H Lin; W-L Lin; H-C Chen; J-Y Wu; M C-H Lee; C-C Lee
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-01-21       Impact factor: 3.267

7.  An investigation of the risk factors for infection with methicillin-resistant Staphylococcus aureus among patients in a neonatal intensive care unit.

Authors:  Haruyo Sakaki; Midori Nishioka; Katsuya Kanda; Yasuko Takahashi
Journal:  Am J Infect Control       Date:  2009-06-17       Impact factor: 2.918

Review 8.  Septic arthritis of the pubic symphysis: review of 100 cases.

Authors:  John J Ross; Linden T Hu
Journal:  Medicine (Baltimore)       Date:  2003-09       Impact factor: 1.889

9.  Post-Partum Diastasis of the Pubic Symphysis: Report of a Rare Case.

Authors:  Jeevitha Kamakoti Jayaraman; Prabha Ganapathy; Nalliannan Indira
Journal:  J Clin Diagn Res       Date:  2015-09-01

10.  Postpartum sacral insufficiency fractures.

Authors:  Charles Xiao Bo Yan; Line Vautour; Marie-Hélène Martin
Journal:  Skeletal Radiol       Date:  2015-11-10       Impact factor: 2.199

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  5 in total

1.  Postpartum septic symphysitis, a rare condition with possible long-term consequences: a cohort study with long-term follow-up.

Authors:  Helen Elden; Monika Fagevik Olsen; Nasrin Farah Hussein; Lisa Wibeck Axelsson; Verena Sengpiel; Michael Ullman
Journal:  BMC Pregnancy Childbirth       Date:  2021-11-16       Impact factor: 3.007

Review 2.  Peripartum Pubic Symphysis Diastasis-Practical Guidelines.

Authors:  Artur Stolarczyk; Piotr Stępiński; Łukasz Sasinowski; Tomasz Czarnocki; Michał Dębiński; Bartosz Maciąg
Journal:  J Clin Med       Date:  2021-05-31       Impact factor: 4.241

3.  Incremental Value of Three-Phase Bone Scintigraphy and Single-Photon Emission Computed Tomography-Computed Tomography in a Case of Postpartum PUO in the Wake of The Antibiotic-Resistance Era.

Authors:  Pramukh Kulkarni; Indirani M Elangoven; A Jaykanth; Shelley Simon
Journal:  Indian J Nucl Med       Date:  2021-03-04

4.  Surgical debridement of infected pubic symphysitis supports optimal outcome.

Authors:  Benjamin Devlieger; Daniel Wagner; Johannes Hopf; Pol Maria Rommens
Journal:  Arch Orthop Trauma Surg       Date:  2020-08-14       Impact factor: 3.067

5.  Orthopedic management of pubic symphysis osteomyelitis: a case series.

Authors:  Henry T Shu; Ahmed H Elhessy; Janet D Conway; Arthur L Burnett; Babar Shafiq
Journal:  J Bone Jt Infect       Date:  2021-07-16
  5 in total

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