Elena Gonzalez Rodriguez1,2, Mirah Stuber3, Cinzia Del Giovane3, Martin Feller3,4, Tinh-Hai Collet2, Axel L Löwe3,4, Manuel R Blum4, Nicolien A van Vliet5, Diana van Heemst5, Patricia M Kearney6, Jacobijn Gussekloo7, Simon Mooijaart7, Rudi G J Westendorp8, David J Stott9, Daniel Aeberli10, Douglas C Bauer11, Didier Hans1, Nicolas Rodondi3,4. 1. Center of Bone Diseases, Rheumatology Unit, Bone and Joint Department, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. 2. Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. 3. Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland. 4. Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. 5. Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands. 6. School of Public Health, University College Cork, Cork, Ireland. 7. Departments of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands. 8. Department of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark. 9. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. 10. Department of Rheumatology and Clinical Immunology/Allergology, Inselspital, Bern University Hospital, Bern, Switzerland. 11. Departments of Medicine, Epidemiology and Biostatistics, University of California, San Francisco, US.