Wei Huang1, Xuan Gong2, Steve Sandiford1,3, Xiaoqiang He1,4, Feilong Li1,5, Yuwan Li1, Ziming Liu1, Leilei Qin1, Jianye Yang1, Sizheng Zhu1, Jiawei Wang1, Xiaolin Tu6, Lei Ye7, Ning Hu1. 1. Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. 2. Department of Outpatient, Chongqing General Hospital, Chongqing, 400013, China. 3. Department of Orthopedics, Queen Elizabeth Hospital, Bridgetown, Barbados. 4. Department of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. 5. Department of Orthopedics, Chongqing Dazu People's Hospital, Chongqing 402360, China. 6. Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing 400016, China. 7. Chongqing Runze Pharmaceutical Co. Ltd., Chongqing 401120, China.
Abstract
BACKGROUND: Tantalum rods have been used in osteonecrosis of the femoral head (ONFH) for several years, while Zimmer trabecular metal implants have been proposed as the best choice. The aim of this study was to evaluate the effect of a new porous tantalum rod on the treatment of early ONFH. METHODS: From July 2014 to December 2015, 19 patients (21 hips) were treated with Runze tantalum rod, and 20 patients (20 hips) received Zimmer tantalum prosthesis. All patients were followed up for at least 3 years. RESULTS: There was no significant difference in demographic characteristics and the Harris Hip Score (HHS) improvement between the two groups. Kaplan-Meier analysis did not show any statistically significant difference in survival rates. One case in the Runze group had persistent pain and required conversion to total hip arthroplasty (THA) 8 months post-surgery. Histological evaluations revealed the presence of abundant new bone ingrowth into pores of the tantalum. The osteonecrosis observed in other patients was almost unchanged. At final follow-up, progressive collapse of the femoral head or the apparent joint space narrowing had not occurred. CONCLUSIONS: Compared with the traditional implants, implantation of the Chinese tantalum rod in the treatment of Association Research Circulation Osseous (ARCO) stages I, and II ONFH demonstrated highly encouraging clinical results. 2019 Annals of Translational Medicine. All rights reserved.
BACKGROUND: Tantalum rods have been used in osteonecrosis of the femoral head (ONFH) for several years, while Zimmer trabecular metal implants have been proposed as the best choice. The aim of this study was to evaluate the effect of a new porous tantalum rod on the treatment of early ONFH. METHODS: From July 2014 to December 2015, 19 patients (21 hips) were treated with Runze tantalum rod, and 20 patients (20 hips) received Zimmer tantalum prosthesis. All patients were followed up for at least 3 years. RESULTS: There was no significant difference in demographic characteristics and the Harris Hip Score (HHS) improvement between the two groups. Kaplan-Meier analysis did not show any statistically significant difference in survival rates. One case in the Runze group had persistent pain and required conversion to total hip arthroplasty (THA) 8 months post-surgery. Histological evaluations revealed the presence of abundant new bone ingrowth into pores of the tantalum. The osteonecrosis observed in other patients was almost unchanged. At final follow-up, progressive collapse of the femoral head or the apparent joint space narrowing had not occurred. CONCLUSIONS: Compared with the traditional implants, implantation of the Chinese tantalum rod in the treatment of Association Research Circulation Osseous (ARCO) stages I, and II ONFH demonstrated highly encouraging clinical results. 2019 Annals of Translational Medicine. All rights reserved.
Entities:
Keywords:
Porous tantalum rod; early stage; femoral head; osteonecrosis; total hip arthroplasty (THA)
Authors: A K Tsao; J R Roberson; M J Christie; D D Dore; D A Heck; D D Robertson; R A Poggie Journal: J Bone Joint Surg Am Date: 2005 Impact factor: 5.284
Authors: Emilios E Pakos; Panayiotis Megas; Nikolaos K Paschos; Spyridon A Syggelos; Antonios Kouzelis; Georgios Georgiadis; Theodoros A Xenakis Journal: World J Orthop Date: 2015-11-18