| Literature DB >> 31699555 |
Vaibhao Kisanrao Lule1, Sudhir Kumar Tomar2, Prince Chawla3, Sarang Pophaly4, Suman Kapila5, Sumit Arora5.
Abstract
The present study utilizes lactobacilli strains having the potential to accumulate a significant amount of Zinc (Zn) in their biomass and ability to deliver the same mineral in a highly bioavailable form. A human origin Lactobacillus fermentum SR4 and Lactobacillus rhamnosus GG (LGG) were studied for their ability to accumulate Zn by growing them in the medium containing Zn salt. Further, Zn enriched cell lysates were prepared by Ultrasonication, as an organic Zn source. Various functional groups involved in bacterial Zn binding were identified by FT-IR spectroscopy and elemental Zn in bio-chelated cell lysate complex was confirmed by SEM and Energy Dispersive X-ray Spectrometry (EDX). Experimental data demonstrated a significantly higher (P < 0.05) bioavailability of Zn chelated by SR4 followed by LGG i.e., 57% and 48%, as compared to the commercially available inorganic (ZnSo4) and even organic (Zinc gluconate) forms tested which has 15.6% and 21.7% respectively.Entities:
Keywords: Bioavailability; Caco-2 cell; Lactobacillus; Scanning electron microscopy; Zinc
Mesh：
Substances：
Year: 2019 PMID： 31699555 DOI： 10.1016/j.foodchem.2019.125583
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514