| Literature DB >> 31699080 |
Tayyaba Afsar1, Suhail Razak2,3, Ali Almajwal4, Muhammad Rashid Khan1.
Abstract
Following publication of the original article [1], the author reported that Tables 3 and 4 were incorrect due to a production error.Entities:
Year: 2019 PMID: 31699080 PMCID: PMC6839164 DOI: 10.1186/s12906-019-2658-6
Source DB: PubMed Journal: BMC Complement Altern Med ISSN: 1472-6882 Impact factor: 3.659
Effect of cisplatin (CP) and different treatments of AHE on lung tissue antioxidant enzymes
| Group | POD | SOD | CAT | QR |
|---|---|---|---|---|
| Control | 9.56 ± 0.635b | 1.366 ± 0.038b | 18.48 ± 0.058b | 128.2 ± 0.81b |
| CP | 5.03 ± 0.271a | 0.765 ± 0.019a | 10.83 ± 0.049a | 83.99 ± 0.486a |
| AHE alone | 10.29 ± 0.314b | 1.358 ± 0.058b | 18.57 ± 0.057b | 128.9 ± 0.179b |
| CP + AHE | 6.22 ± 0.128a, d | 0.982 ± 0.035a,b*,d** | 14.15 ± 0.083a,b, d | 98.82 ± 1.232a.b, d |
| AHE + CP | 9.18 ± 0.185b, c | 1.255 ± 0.038b,c** | 17.07 ± 0.026a,b, c | 119.5 ± 1.283a,b, c |
| CP + Sily | 9.20 ± 0.208b | 1.262 ± 0.021b | 17.14 ± 0.081a,b | 119.9 ± 1.008a,b |
Values expressed as mean ± SEM. a Significance at p < 0.0001 Vs. control group, b Significance at p < 0.0001 Vs. Cisplatin (CP) group. c Significance at p < 0.0001 of AHE + CP pre-treated group Vs. CP + AHE post-treated group. d Significance at p < 0.0001 of CP + AHE treatment groups Vs CP + Sily group. *, **: Significant difference at p < 0.001. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)
Effect of cisplatin (CP) and different treatments of AHE on lungs tissue antioxidant enzymes and GSH profile
| Group | GSH | GR | GST | γ-GT | GPx |
|---|---|---|---|---|---|
| Control | 16.12 ± 0.578b | 143.7 ± 1.342b | 98.85 ± 0.918b | 295.4 ± 1.113b | 107.4 ± 0.730b |
| CP | 8.334 ± 0.356a | 98.02 ± 0.619a | 68.17 ± 0.962a | 82.82 ± 0.958a | 54.08 ± 0.909a |
| AHE alone | 6.38 ± 0.207b | 144.0 ± 1.492b | 99.79 ± 1.865 b | 295.6 ± 0.599b | 108.8 ± 1.216b |
| CP + AHE | 11.99 ± 0.305a,b, d | 116.9 ± 0.813a,b,d | 78.34 ± 1.076a,b**,d** | 137.8 ± 1.017a,b,d | 71.28.8 ± 0.501a,b,c |
| AHE + CP | 15.63 ± 0.532b, c | 135.0 ± 0.393 a,b,c | 89.65 ± 1.49 a**,b,c | 261.4 ± 0.802a,b,c | 92.78 ± 1.216a,b,c |
| CP + Sily | 15.29 ± 0.312b | 133.8 ± 1.25 a,b | 87.60 ± 1.644a,b | 264.3 ± 1.067a,b | 95.64 ± 1.573a,b |
Values expressed as mean ± SEM. a Significance at p < 0.0001 Vs. control group, b Significance at p < 0.0001 Vs. Cisplatin (CP) group. c Significance at p < 0.0001 of AHE + CP pre-treated group Vs. CP + AHE post-treated group. d Significance at p < 0.0001 of CP + AHE treatment groups Vs CP + Sily group. *, **: Significant difference at p < 0.001. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)