Literature DB >> 31697591

Parental Attitudes Toward Deep Brain Stimulation in Adolescents with Treatment-Resistant Conditions.

Eric A Storch1, Sandra L Cepeda1, Eric Lee1, Sarah L V Goodman1, Anthony D Robinson2, Alessandro S De Nadai2, Sophie C Schneider1, Sameer A Sheth3, Laura Torgerson4, Gabriel Lázaro-Muñoz4.   

Abstract

Objective: To examine parent's perceptions of deep brain stimulation (DBS) and whether DBS is perceived to be a viable and safe treatment for their adolescent child presenting with a severe, treatment-resistant neurological or psychiatric condition. Method: Two hundred and seventy-nine parents completed an online survey using Amazon Mechanical Turk (MTurk). Participants were presented with five vignette scenarios involving adolescents with severe, treatment-resistant neurological or psychiatric conditions: Rett syndrome, autism spectrum disorder, epilepsy, obsessive-compulsive disorder, and Tourette syndrome. Parents were then asked to evaluate each scenario and rate overall acceptability of using DBS to improve their child's core symptoms. Data were collected over a period of 2 weeks in the month of October 2018.
Results: We found that parents reported favorable impressions of DBS regardless of the target condition, especially when greater improvement could be assured and when their child had the capacity to assist in the treatment decision-making. Parents indicated some reluctance to use DBS when possible safety concerns were present. Familiarity with DBS was directly associated with attitudes. Conclusions: The findings highlight an overall parental willingness to consider DBS as a treatment option for key symptoms of neurological and psychiatric conditions in adolescents.

Entities:  

Keywords:  Tourette; adolescents; autism spectrum disorder; deep brain stimulation; neuroethics; obsessive-compulsive disorder

Mesh:

Year:  2019        PMID: 31697591      PMCID: PMC7047254          DOI: 10.1089/cap.2019.0134

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN: 1044-5463            Impact factor:   2.576


  11 in total

Review 1.  Current and future indications for deep brain stimulation in pediatric populations.

Authors:  Nir Lipsman; Michael Ellis; Andres M Lozano
Journal:  Neurosurg Focus       Date:  2010-08       Impact factor: 4.047

2.  Letter: Evaluating Risks and Benefit of Deep Brain Stimulation for Treatment-Refractory Tourette Syndrome.

Authors:  Carly Johnco; Eric A Storch
Journal:  Neurosurgery       Date:  2016-05       Impact factor: 4.654

3.  Patient Preferences and Acceptability of Evidence-Based and Novel Treatments for Obsessive-Compulsive Disorder.

Authors:  Sapana R Patel; Hanga Galfavy; Marcia B Kimeldorf; Lisa B Dixon; Helen Blair Simpson
Journal:  Psychiatr Serv       Date:  2016-10-17       Impact factor: 3.084

4.  Pallidal deep brain stimulation for primary dystonia in children.

Authors:  Abilash Haridas; Michele Tagliati; Irene Osborn; Ioannis Isaias; Yakov Gologorsky; Susan B Bressman; Donald Weisz; Ron L Alterman
Journal:  Neurosurgery       Date:  2011-03       Impact factor: 4.654

5.  Deep brain stimulation for pediatric dystonia: a meta-analysis with individual participant data.

Authors:  Lior M Elkaim; Naif M Alotaibi; Alissa Sigal; Haifa M Alotaibi; Nir Lipsman; Suneil K Kalia; Darcy L Fehlings; Andres M Lozano; George M Ibrahim
Journal:  Dev Med Child Neurol       Date:  2018-10-15       Impact factor: 5.449

6.  A systematic review of deep brain stimulation for the treatment of drug-resistant epilepsy in childhood.

Authors:  Han Yan; Eric Toyota; Melanie Anderson; Taylor J Abel; Elizabeth Donner; Suneil K Kalia; James Drake; James T Rutka; George M Ibrahim
Journal:  J Neurosurg Pediatr       Date:  2018-11-30       Impact factor: 2.375

Review 7.  Historical developments in children's deep brain stimulation.

Authors:  Laura Cif; Philippe Coubes
Journal:  Eur J Paediatr Neurol       Date:  2016-09-07       Impact factor: 3.140

8.  Neuroethics of Neuromodulation: An Update.

Authors:  Peter Zuk; Laura Torgerson; Demetrio Sierra-Mercado; Gabriel Lázaro-Muñoz
Journal:  Curr Opin Biomed Eng       Date:  2018-10-26

Review 9.  Deep brain stimulation for pediatric movement disorders.

Authors:  Warren A Marks; John Honeycutt; Fernando Acosta; Maryann Reed
Journal:  Semin Pediatr Neurol       Date:  2009-06       Impact factor: 1.636

10.  Would you be willing to zap your child's brain? Public perspectives on parental responsibilities and the ethics of enhancing children with transcranial direct current stimulation.

Authors:  Katy Wagner; Hannah Maslen; Justin Oakley; Julian Savulescu
Journal:  AJOB Empir Bioeth       Date:  2018-02-08
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  2 in total

1.  Perceptions of Deep Brain Stimulation for Adolescents with Obsessive-Compulsive Disorder.

Authors:  Saira A Weinzimmer; Sophie C Schneider; Sandra L Cepeda; Andrew G Guzick; Gabriel Lázaro-Muñoz; Elizabeth McIngvale; Wayne K Goodman; Sameer A Sheth; Eric A Storch
Journal:  J Child Adolesc Psychopharmacol       Date:  2021-02-02       Impact factor: 2.576

2.  Medical Students' Knowledge and Perception of Deep Brain Stimulation.

Authors:  Brian F Saway; Sanaz Monjazeb; Kerilyn Godbe; Tessa Anwyll; Anita Kablinger; Mark Witcher
Journal:  J Med Educ Curric Dev       Date:  2021-03-02
  2 in total

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