| Literature DB >> 31695957 |
Hyunnho Cho1, Kyong Kim1, Dae-Ja Jang1, Hye Young Kim1.
Abstract
Glucagon like peptide-1 (GLP-1) plays a major role in the regulation of energy homeostasis as it causes satiety and suppresses appetite. Angelica dahurica, Coreanomecon hylomeconoides, Chrysanthemum morifolium, Portulaca oleracea, Stellaria alsine, and Stellaria media have traditionally been used as famine relief foods in Korea. The aim of the present study was to determine whether the aqueous ethanolic extracts of the six plants stimulate GLP-1 secretion. The results demonstrated that each extract of the plants stimulated GLP-1 secretion from enteroendocrine NCI-H716 cells, respectively. Among the extracts examined, the extract of Portulaca oleracea showed the highest activity on GLP-1 release. The results may suggest that the GLP-1 secretion induced by the six plants is a possible mechanism for the six plants exerting effects on satiety increase and appetite suppression. © The Korean Society of Food Science and Technology 2019.Entities:
Keywords: Enteroendocrine cells; Famine relief foods; Glucagon like peptide-1; Portulaca oleracea; Satiety
Year: 2019 PMID： 31695957 PMCID： PMC6811474 DOI： 10.1007/s10068-019-00603-x
Source DB: PubMed Journal: Food Sci Biotechnol ISSN： 1226-7708 Impact factor: 2.391