Literature DB >> 31695738

Intensive care for organ preservation: A four-stage pathway.

Dale Gardiner1, David M Shaw2,3, Jack K Kilcullen4, Anne L Dalle Ave5.   

Abstract

OBJECTIVE: Intensive care for organ preservation (ICOP) is defined as the initiation or pursuit of intensive care not to save the patient's life, but to protect and optimize organs for transplantation. ANALYSIS: When a patient has devastating brain injury that might progress to organ donation this can be conceptualized as evolving through four consecutive stages: (1) instability, (2) stability, (3) futility and (4) finality. ICOP might be applied at any of these stages, raising different ethical issues. Only in the stage of finality is the switch from neurointensive care to ICOP ethically justified.
CONCLUSION: The difference between the stages is that during instability, stability and futility the focus must be neurointensive care which seeks the patient's recovery or an accurate neurological prognostication, while finality focuses on withdrawal of life-sustaining therapy and commencement of comfort care, which may include ICOP for deceased donation. © The Intensive Care Society 2019.

Entities:  

Keywords:  Transplantation; brain death; ethics; intensive care; organ donation; organ preservation

Year:  2019        PMID: 31695738      PMCID: PMC6820229          DOI: 10.1177/1751143719840254

Source DB:  PubMed          Journal:  J Intensive Care Soc        ISSN: 1751-1437


  28 in total

1.  Increased transplanted organs from the use of a standardized donor management protocol.

Authors:  John D Rosendale; Franki L Chabalewski; Maureen A McBride; Edward R Garrity; Bruce R Rosengard; Francis L Delmonico; H Myron Kauffman
Journal:  Am J Transplant       Date:  2002-09       Impact factor: 8.086

2.  Non-therapeutic (elective) ventilation of potential organ donors: the ethical basis for changing the law.

Authors:  A B Shaw
Journal:  J Med Ethics       Date:  1996-04       Impact factor: 2.903

3.  Organ transplant initiatives: the twilight zone.

Authors:  D P Price
Journal:  J Med Ethics       Date:  1997-06       Impact factor: 2.903

4.  The ethics of elective ventilation.

Authors:  Michael Monette
Journal:  CMAJ       Date:  2012-10-09       Impact factor: 8.262

Review 5.  Recommendations for the Critical Care Management of Devastating Brain Injury: Prognostication, Psychosocial, and Ethical Management : A Position Statement for Healthcare Professionals from the Neurocritical Care Society.

Authors:  Michael J Souter; Patricia A Blissitt; Sandralee Blosser; Jordan Bonomo; David Greer; Draga Jichici; Dea Mahanes; Evie G Marcolini; Charles Miller; Kiranpal Sangha; Susan Yeager
Journal:  Neurocrit Care       Date:  2015-08       Impact factor: 3.210

6.  Is providing elective ventilation in the best interests of potential donors?

Authors:  Andrew John McGee; Benjamin Peter White
Journal:  J Med Ethics       Date:  2013-01-15       Impact factor: 2.903

Review 7.  Extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation or uncontrolled donation after the circulatory determination of death following out-of-hospital refractory cardiac arrest-An ethical analysis of an unresolved clinical dilemma.

Authors:  Anne L Dalle Ave; David M Shaw; Dale Gardiner
Journal:  Resuscitation       Date:  2016-07-20       Impact factor: 5.262

8.  Cranioplasty with bandaging. New forms of limitation of life support and organ donation.

Authors:  D Escudero; L Cofiño; D Gracia; M Palacios; M Casares; L Cabré; P Simón; P Miranda; K Martínez; S Iribarren; I Saralegui; R M Simó; B de León; V Español
Journal:  Med Intensiva       Date:  2013-03-07       Impact factor: 2.491

9.  Advance statement of consent from patients with primary CNS tumours to organ donation and elective ventilation.

Authors:  Umang Jash Patel
Journal:  J Med Ethics       Date:  2013-01-08       Impact factor: 2.903

10.  In situ normothermic regional perfusion for controlled donation after circulatory death--the United Kingdom experience.

Authors:  G C Oniscu; L V Randle; P Muiesan; A J Butler; I S Currie; M T P R Perera; J L Forsythe; C J E Watson
Journal:  Am J Transplant       Date:  2014-10-03       Impact factor: 8.086

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