Literature DB >> 31695526

A qualitative study of patient perspectives related to glucocorticoid therapy in polymyalgia rheumatica and giant cell arteritis.

Elizabeth Hoon1, Carlee Ruediger2,3, Tiffany K Gill2, Rachel J Black2,4, Catherine L Hill2,3,4.   

Abstract

OBJECTIVE: To determine patient experiences of glucocorticoid (GC) therapy in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA).
METHODS: Patients with a diagnosis of PMR or GCA were invited to participate in this qualitative study that used focus groups to explore: symptoms onset, process of diagnosis, treatment, adverse effects (AEs), and ongoing condition/s management. Data were transcribed verbatim and a "framework" approach was used for analysis and interpretation.
RESULTS: Fourteen patients participated. Weight gain, changes in face and neck shape, and bruising were commonly reported and impacts of these AEs on quality of life were highlighted. Dealing with uncertainties associated with long-term experiences of the condition/s and cycles of GC treatment were raised as were workload demands for patients in managing both the condition and other people's expectations and recommendations related to GC therapy.
CONCLUSION: These findings demonstrate that the patient experience of GC use is poorly captured by usual physician monitoring for GC AEs. These findings suggest that development of a patient-reported outcome instrument for inflammatory conditions treated with GCs is required.
© 2019 Hoon et al.

Entities:  

Keywords:  adverse effects; giant cell arteritis; glucocorticoid therapy; patient experience; polymyalgia rheumatica

Year:  2019        PMID: 31695526      PMCID: PMC6718238          DOI: 10.2147/OARRR.S213964

Source DB:  PubMed          Journal:  Open Access Rheumatol        ISSN: 1179-156X


  11 in total

Review 1.  Polymyalgia rheumatica and giant-cell arteritis.

Authors:  Carlo Salvarani; Fabrizio Cantini; Luigi Boiardi; Gene G Hunder
Journal:  N Engl J Med       Date:  2002-07-25       Impact factor: 91.245

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Review 4.  Polymyalgia rheumatica: clinical update.

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5.  A Patient-reported Outcome Measure for Effect of Glucocorticoid Therapy in Adults with Inflammatory Diseases Is Needed: Report from the OMERACT 2016 Special Interest Group.

Authors:  Rachel J Black; Joanna C Robson; Susan M Goodman; Elizabeth Hoon; Lana Y H Lai; Lee S Simon; Eileen Harrison; Lorna Neill; Pam Richards; Linda M Nelsen; J Michael Nebesky; Sarah L Mackie; Catherine L Hill
Journal:  J Rheumatol       Date:  2017-04-01       Impact factor: 4.666

6.  Use of oral corticosteroids in the community and the prevention of secondary osteoporosis: a cross sectional study.

Authors:  L J Walsh; C A Wong; M Pringle; A E Tattersfield
Journal:  BMJ       Date:  1996-08-10

Review 7.  Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data.

Authors:  J A P Da Silva; J W G Jacobs; J R Kirwan; M Boers; K G Saag; L B S Inês; E J P de Koning; F Buttgereit; M Cutolo; H Capell; R Rau; J W J Bijlsma
Journal:  Ann Rheum Dis       Date:  2005-08-17       Impact factor: 19.103

Review 8.  Adverse events of low- to medium-dose oral glucocorticoids in inflammatory diseases: a meta-analysis.

Authors:  J N Hoes; J W G Jacobs; S M M Verstappen; J W J Bijlsma; G J M G Van der Heijden
Journal:  Ann Rheum Dis       Date:  2008-12-09       Impact factor: 19.103

Review 9.  Polymyalgia rheumatica and giant-cell arteritis.

Authors:  Carlo Salvarani; Fabrizio Cantini; Gene G Hunder
Journal:  Lancet       Date:  2008-07-19       Impact factor: 79.321

10.  Using the framework method for the analysis of qualitative data in multi-disciplinary health research.

Authors:  Nicola K Gale; Gemma Heath; Elaine Cameron; Sabina Rashid; Sabi Redwood
Journal:  BMC Med Res Methodol       Date:  2013-09-18       Impact factor: 4.615

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Review 2.  Reducing the Toxicity of Long-Term Glucocorticoid Treatment in Large Vessel Vasculitis.

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Journal:  Curr Rheumatol Rep       Date:  2020-10-12       Impact factor: 4.592

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