Literature DB >> 31695269

Bisphosphonate associated femoral stress fracture distal to an orthopaedic implant: They are predictable!

Gunasekaran Kumar1, Anoop C Dhamangaonkar1,2.   

Abstract

Stress fractures are uncommon and often occur in young athletes with high intensity physical activity. These stress fractures occur in weight bearing long bones. Recent literature suggests association of thigh pain, tension side cortical thickening of femoral shaft or a femoral subtrochanteric atypical stress fractures in patients on long term bisphosphonate therapy. The reports of peri-implant bisphosphonate associated atypical stress fractures are very rare. We describe a series of three cases of femoral shaft stress phenomenon around orthopaedic implants who presented with similar prodromal thigh pain and tension side cortical thickening. Two patients sustained fractures as the condition was not recognised despite presenting with prodromal symptoms and one patient with a stress riser who was treated prophylactically. Thus this series aims to highlight the importance of identifying the stress phenomenon around orthopaedic implants, be it intra or extra-medullary implants. The location of these fractures is just distal to the implants and are classically transverse fractures. The treatment of peri-implant stress fractures needs a personalised approach in every case with appropriate choice of implants.
© 2019 Delhi Orthopedic Association. All rights reserved.

Entities:  

Keywords:  Bisphosphonate; Dynamic hip screw; Stress fracture; Total hip replacement

Year:  2019        PMID: 31695269      PMCID: PMC6823695          DOI: 10.1016/j.jcot.2019.01.006

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN: 0976-5662


  17 in total

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Authors:  F PAUWELS
Journal:  Acta Anat (Basel)       Date:  1951

2.  A rare case of a bisphosphonate-induced peri-prosthetic femoral fracture.

Authors:  M B Cross; D Nam; M C H van der Meulen; M P G Bostrom
Journal:  J Bone Joint Surg Br       Date:  2012-07

3.  Periprosthetic Fracture of the Femur After Long-Term Bisphosphonate Use: A Case Report.

Authors:  Foster Chen; Timothy Bhattacharyya
Journal:  JBJS Case Connect       Date:  2012 Apr-Jun

4.  Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution.

Authors:  S-K Goh; K Y Yang; J S B Koh; M K Wong; S Y Chua; D T C Chua; T S Howe
Journal:  J Bone Joint Surg Br       Date:  2007-03

5.  Bisphosphonate use and atypical fractures of the femoral shaft.

Authors:  Jörg Schilcher; Karl Michaëlsson; Per Aspenberg
Journal:  N Engl J Med       Date:  2011-05-05       Impact factor: 91.245

6.  Long-Term Alendronate Use Not without Consequences?

Authors:  M P Somford; G F A E Geurts; J W A M den Teuling; B J W Thomassen; W F Draijer
Journal:  Int J Rheumatol       Date:  2010-01-27

7.  Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital.

Authors:  Kuntheavy Ing-Lorenzini; Jules Desmeules; Olivier Plachta; Domizio Suva; Pierre Dayer; Robin Peter
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

8.  Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility.

Authors:  Matthijs P Somford; Frits W Draijer; Bregje J W Thomassen; Pascale M Chavassieux; Georges Boivin; Socrates E Papapoulos
Journal:  J Bone Miner Res       Date:  2009-10       Impact factor: 6.741

9.  Femoral cortical stress lesions in long-term bisphosphonate therapy: a herald of impending fracture?

Authors:  Joyce S B Koh; Seo Kiat Goh; Meng Ai Png; Ernest B K Kwek; Tet Sen Howe
Journal:  J Orthop Trauma       Date:  2010-02       Impact factor: 2.512

10.  Bisphosphonate-associated peri-implant fractures: a new clinical entity? A series of 10 patients with 11 fractures.

Authors:  Justine Yun Yu Lee; Tamara Soh; Tet Sen Howe; Joyce Suang Bee Koh; Ernest Beng Kee Kwek; David Thai Chong Chua
Journal:  Acta Orthop       Date:  2015       Impact factor: 3.717

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