| Literature DB >> 31693967 |
Xuli Zhang1, Peibing Zheng1, Jérôme J Devaux2, Yan Wang1, Chen Liu1, Jing Li3, Shougang Guo4, Yan Song5, Qian Wang5, Xungang Feng6, Yuzhong Wang7.
Abstract
Patients with chronic inflammatory demyelinating polyneuropathy (CIDP) seropositive for autoantibodies against nodal and paranodal proteins display distinct clinical presentations. We herein tested for autoantibodies against neurofascin (NF) 155, NF186, contactin-associated protein 1 and contactin-1 and investigated the autoantibody-related clinical features in 29 patients with CIDP from China. Six patients with anti-NF155 IgG4 antibodies displayed younger age of onset and poor response to intravenous immunoglobulin than seronegative patients. One patient had anti-NF186 IgG antibody and no patients had anti-contactin-associated protein 1 or anti-contactin-1 antibodies. Clinical features of CIDP patients with anti-NF155 antibodies in China were similar to those reported in other countries.Entities:
Keywords: Autoantibody; Chronic inflammatory demyelinating polyneuropathy; Clinical features; Nodal protein
Mesh：
Substances：
Year: 2019 PMID： 31693967 DOI： 10.1016/j.jneuroim.2019.577074
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478