Literature DB >> 31688445

Does Retinal Ganglion Cell Loss Precede Visual Field Loss in Glaucoma?

Donald C Hood1,2.   

Abstract

It is often said that substantial retinal ganglion cells are lost before glaucomatous damage is detected by standard automated perimetry. There are 4 key articles referenced to support this belief. To test the hypothesis that the 4 key articles are incorrectly cited, the publications in the first 6 months of 2019 that reference 1 or more of these 4 articles were examined. In particular, the degree to which the quotes from these 2019 publications accurately reflected the evidence in the 4 key articles was assessed. These quotes are inadequately supported by the data, and in some cases even by the conclusions found in the abstracts of the key articles. This is despite several review articles that have questioned the evidence in these key articles. Further, a case can be made that the evidence in the key articles better supports the opposite conclusion. That is, the data suggest that sensitivity loss can be seen on standard automated perimetry before retinal ganglion cells are missing.

Entities:  

Mesh:

Year:  2019        PMID: 31688445      PMCID: PMC7343057          DOI: 10.1097/IJG.0000000000001380

Source DB:  PubMed          Journal:  J Glaucoma        ISSN: 1057-0829            Impact factor:   2.503


  35 in total

1.  Reading Ability in Primary Open-angle Glaucoma: Evaluation with Radner Reading Charts.

Authors:  Teresa Rolle; Laura Dallorto; Riccardo Cafasso; Roberto Mazzocca; Daniela Curto; Raffaele Nuzzi
Journal:  Optom Vis Sci       Date:  2019-01       Impact factor: 1.973

2.  Discriminating performance of macular ganglion cell-inner plexiform layer thicknesses at different stages of glaucoma.

Authors:  Melih Ustaoglu; Nilgun Solmaz; Feyza Onder
Journal:  Int J Ophthalmol       Date:  2019-03-18       Impact factor: 1.779

Review 3.  The role of optical coherence tomography in the evaluation of compressive optic neuropathies.

Authors:  Jonathan A Micieli; Nancy J Newman; Valérie Biousse
Journal:  Curr Opin Neurol       Date:  2019-02       Impact factor: 5.710

4.  Subcortical visual pathway may be a new way for early diagnosis of glaucoma.

Authors:  Yi Sun; Wenbin Huang; Fei Li; Hao Li; Liping Wang; Yan Huang; Xiulan Zhang
Journal:  Med Hypotheses       Date:  2018-12-27       Impact factor: 1.538

5.  Longitudinal Macular Structure-Function Relationships in Glaucoma and Their Sources of Variability.

Authors:  Kouros Nouri-Mahdavi; Nima Fatehi; Joseph Caprioli
Journal:  Am J Ophthalmol       Date:  2019-05-10       Impact factor: 5.258

6.  Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry.

Authors:  Patricio G Schlottmann; Stefano De Cilla; David S Greenfield; Joseph Caprioli; David F Garway-Heath
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-06       Impact factor: 4.799

7.  Imaging and quantifying ganglion cells and other transparent neurons in the living human retina.

Authors:  Zhuolin Liu; Kazuhiro Kurokawa; Furu Zhang; John J Lee; Donald T Miller
Journal:  Proc Natl Acad Sci U S A       Date:  2017-11-14       Impact factor: 11.205

8.  Autoantibody Biomarker Discovery in Primary Open Angle Glaucoma Using Serological Proteome Analysis (SERPA).

Authors:  Vanessa M Beutgen; Natarajan Perumal; Norbert Pfeiffer; Franz H Grus
Journal:  Front Immunol       Date:  2019-03-07       Impact factor: 7.561

9.  Loss of retinal ganglion cells in a new genetic mouse model for primary open-angle glaucoma.

Authors:  Sabrina Reinehr; Dennis Koch; Maximilian Weiss; Franziska Froemel; Christina Voss; H Burkhard Dick; Rudolf Fuchshofer; Stephanie C Joachim
Journal:  J Cell Mol Med       Date:  2019-05-29       Impact factor: 5.310

10.  Structure-Function Agreement Is Better Than Commonly Thought in Eyes With Early Glaucoma.

Authors:  Donald C Hood; Emmanouil Tsamis; Nikhil K Bommakanti; Devon B Joiner; Lama A Al-Aswad; Dana M Blumberg; George A Cioffi; Jeffrey M Liebmann; Carlos G De Moraes
Journal:  Invest Ophthalmol Vis Sci       Date:  2019-10-01       Impact factor: 4.799

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  8 in total

1.  Predictive value of macular ganglion cell-inner plexiform layer thickness in visual field defect of pituitary adenoma patients: a case-control study.

Authors:  Li Xia; Jia Wenhui; Yang Xiaowen; Xie Wenfang; Zhang Wei; Hu Yanjun; Peng Xiaoyan
Journal:  Pituitary       Date:  2022-07-14       Impact factor: 3.599

2.  Long-term retinal protection by MEK inhibition in Pax6 haploinsufficiency mice.

Authors:  James D Cole; Kara M McHaney; Behnam Rabiee; Jingyi Gao; Carlos Rodriguez; David A Miller; Mingna Liu; Marta Grannonico; Pedro Norat; Hao F Zhang; Ali R Djalilian; Xiaorong Liu
Journal:  Exp Eye Res       Date:  2022-03-01       Impact factor: 3.770

3.  Improving the Detection of Glaucoma and Its Progression: A Topographical Approach.

Authors:  Donald C Hood; Zane Z Zemborain; Emmanouil Tsamis; Carlos Gustavo De Moraes
Journal:  J Glaucoma       Date:  2020-08       Impact factor: 2.290

4.  A Case for the Use of Artificial Intelligence in Glaucoma Assessment.

Authors:  Joel S Schuman; Maria De Los Angeles Ramos Cadena; Rebecca McGee; Lama A Al-Aswad; Felipe A Medeiros
Journal:  Ophthalmol Glaucoma       Date:  2021-12-22

5.  Quantification of Retinal Ganglion Cell Morphology in Human Glaucomatous Eyes.

Authors:  Zhuolin Liu; Osamah Saeedi; Furu Zhang; Ricardo Villanueva; Samuel Asanad; Anant Agrawal; Daniel X Hammer
Journal:  Invest Ophthalmol Vis Sci       Date:  2021-03-01       Impact factor: 4.799

6.  Electrical neurostimulation in glaucoma with progressive vision loss.

Authors:  Carl Erb; Sophie Eckert; Pia Gindorf; Martin Köhler; Thomas Köhler; Lukas Neuhann; Thomas Neuhann; Nadja Salzmann; Stefanie Schmickler; Jens Ellrich
Journal:  Bioelectron Med       Date:  2022-03-31

7.  A Topographic Comparison of OCT Minimum Rim Width (BMO-MRW) and Circumpapillary Retinal Nerve Fiber Layer (cRNFL) Thickness Measures in Eyes With or Suspected Glaucoma.

Authors:  Sol La Bruna; Emmanouil Tsamis; Zane Z Zemborain; Zhichao Wu; Carlos Gustavo De Moraes; Robert Ritch; Donald C Hood
Journal:  J Glaucoma       Date:  2020-08       Impact factor: 2.503

8.  Time Lag Between Functional Change and Loss of Retinal Nerve Fiber Layer in Glaucoma.

Authors:  Stuart K Gardiner; Steven L Mansberger; Brad Fortune
Journal:  Invest Ophthalmol Vis Sci       Date:  2020-11-02       Impact factor: 4.799

  8 in total

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