Literature DB >> 31686230

Benefit-to-Risk Balance of Weight Loss Interventions in Older Adults with Obesity.

Peter R DiMilia1,2,3, Alexander C Mittman1, John A Batsis4,5,6,7,8,9.   

Abstract

PURPOSE OF REVIEW: Obesity in the older adult is a burgeoning health epidemic that leads to increased morbidity, disability, and institutionalization. This review presents a brief overview of geriatric-specific consequences of obesity by highlighting the risks and benefits of intentional weight loss. RECENT
FINDINGS: Intentional weight loss reduces the extent of adiposity-related illnesses, yet the approach in older adults is fraught with challenges. Interventions combining caloric restriction and physical exercise (aerobic and resistance) maximize fat loss and minimize loss of muscle and bone. Interventions are also effective at improving physical function, reducing medication burden, and improving symptomatic osteoarthritis in this population. Approaches can mitigate the risks of isolated caloric restriction on muscle and bone in a safe and effective manner. Effective weight loss strategies should be considered in older adults. While there are potential risks, practical clinical approaches can minimize the potential harms while maximizing their benefits.

Entities:  

Keywords:  Benefits; Obesity; Older adults; Risks

Mesh:

Year:  2019        PMID: 31686230      PMCID: PMC6986769          DOI: 10.1007/s11892-019-1249-8

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN: 1534-4827            Impact factor:   4.810


  124 in total

1.  Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients.

Authors:  Dympna Gallagher; David E Kelley; John Thornton; Lawrence Boxt; Xavier Pi-Sunyer; Edward Lipkin; Ebenezer Nyenwe; Isaiah Janumala; Stanley Heshka
Journal:  Am J Clin Nutr       Date:  2016-11-23       Impact factor: 7.045

2.  Reasons for intentional weight loss, unintentional weight loss, and mortality in older men.

Authors:  S Goya Wannamethee; A Gerald Shaper; Lucy Lennon
Journal:  Arch Intern Med       Date:  2005-05-09

3.  An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.

Authors:  O Johnell; J A Kanis
Journal:  Osteoporos Int       Date:  2006-09-16       Impact factor: 4.507

4.  Morbidity and disability in older persons in the years prior to death.

Authors:  J M Guralnik; A Z LaCroix; L G Branch; S V Kasl; R B Wallace
Journal:  Am J Public Health       Date:  1991-04       Impact factor: 9.308

5.  Obesity and knee osteoarthritis. The Framingham Study.

Authors:  D T Felson; J J Anderson; A Naimark; A M Walker; R F Meenan
Journal:  Ann Intern Med       Date:  1988-07-01       Impact factor: 25.391

Review 6.  Are declining testosterone levels a major risk factor for ill-health in aging men?

Authors:  B B Yeap
Journal:  Int J Impot Res       Date:  2008-11-27       Impact factor: 2.896

7.  Obesity affects nursing-care facility admission among whites but not blacks.

Authors:  Claire A Zizza; Amy Herring; June Stevens; Barry M Popkin
Journal:  Obes Res       Date:  2002-08

8.  Unintentional weight loss: Clinical characteristics and outcomes in a prospective cohort of 2677 patients.

Authors:  Xavier Bosch; Esther Monclús; Ona Escoda; Mar Guerra-García; Pedro Moreno; Neus Guasch; Alfons López-Soto
Journal:  PLoS One       Date:  2017-04-07       Impact factor: 3.240

9.  The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial.

Authors:  Karen C Johnson; George A Bray; Lawrence J Cheskin; Jeanne M Clark; Caitlin M Egan; John P Foreyt; Katelyn R Garcia; Stephen Glasser; Frank L Greenway; Edward W Gregg; Helen P Hazuda; Andrea Hergenroeder; James O Hill; Edward S Horton; John M Jakicic; Robert W Jeffery; Steven E Kahn; William C Knowler; Cora E Lewis; Marsha Miller; Maria G Montez; David M Nathan; Jennifer L Patricio; Anne L Peters; Xavier Pi-Sunyer; Henry J Pownall; David Reboussin; J Bruce Redmon; Helmut Steinberg; Thomas A Wadden; Lynne E Wagenknecht; Rena R Wing; Catherine R Womack; Susan Z Yanovski; Ping Zhang; Ann V Schwartz
Journal:  J Bone Miner Res       Date:  2017-07-28       Impact factor: 6.741

10.  Explaining the decrease in U.S. deaths from coronary disease, 1980-2000.

Authors:  Earl S Ford; Umed A Ajani; Janet B Croft; Julia A Critchley; Darwin R Labarthe; Thomas E Kottke; Wayne H Giles; Simon Capewell
Journal:  N Engl J Med       Date:  2007-06-07       Impact factor: 91.245

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  8 in total

Review 1.  Addressing Obesity to Promote Healthy Aging.

Authors:  Meredith N Roderka; Sadhana Puri; John A Batsis
Journal:  Clin Geriatr Med       Date:  2020-08-16       Impact factor: 3.076

2.  Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity.

Authors:  Svetlana Ukraintseva; Konstantin Arbeev; Matt Duan; Igor Akushevich; Alexander Kulminski; Eric Stallard; Anatoliy Yashin
Journal:  Mech Ageing Dev       Date:  2020-12-16       Impact factor: 5.432

3.  Intensive nutrition counseling as part of a multi-component weight loss intervention improves diet quality and anthropometrics in older adults with obesity.

Authors:  Rima Itani Al-Nimr; K C S Wright; Christina L Aquila; Curtis L Petersen; Tyler L Gooding; John A Batsis
Journal:  Clin Nutr ESPEN       Date:  2020-09-19

4.  Predictors of Clinically Meaningful Gait Speed Response to Caloric Restriction Among Older Adults Participating in Weight Loss Interventions.

Authors:  KaKi Tse; Rebecca H Neiberg; Daniel P Beavers; Stephen B Kritchevsky; Barbara J Nicklas; Dalane W Kitzman; W Jack Rejeski; Stephen P Messier; Kristen M Beavers
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2022-10-06       Impact factor: 6.591

5.  Impact of whey protein supplementation in a weight-loss intervention in rural dwelling adults: A feasibility study.

Authors:  John A Batsis; Curtis L Petersen; Summer B Cook; Rima I Al-Nimr; Tiffany Driesse; Dawna Pidgeon; Roger Fielding
Journal:  Clin Nutr ESPEN       Date:  2021-07-24

Review 6.  Impact of Diet and Exercise on Weight and Cognition in Older Adults: A Rapid Review.

Authors:  John A Batsis; Meredith N Roderka; Vanessa K Rauch; Lillian M Seo; Xingyi Li; Peter R DiMilia; Tyler Gooding; Diane Gilbert-Diamond; Auden C McClure; Robert M Roth
Journal:  Am J Health Promot       Date:  2021-01-08

7.  Changes in Body Composition in Older Adults after a Technology-Based Weight Loss Intervention.

Authors:  J A Batsis; D Shirazi; C L Petersen; M N Roderka; D Lynch; D Jimenez; S B Cook
Journal:  J Frailty Aging       Date:  2022

8.  Estimating heterogeneity of physical function treatment response to caloric restriction among older adults with obesity.

Authors:  Daniel P Beavers; Katherine L Hsieh; Dalane W Kitzman; Stephen B Kritchevsky; Stephen P Messier; Rebecca H Neiberg; Barbara J Nicklas; W Jack Rejeski; Kristen M Beavers
Journal:  PLoS One       Date:  2022-05-05       Impact factor: 3.240

  8 in total

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