| Literature DB >> 31683180 |
Wenjie Zheng1, Gaofeng Wang2, Zhe Zhang1, Zhenguo Wang3, Ke Ma4.
Abstract
In traditional Chinese medicine (TCM), type 2 diabetes mellitus (T2DM) is regarded as Xiao Ke disease. Liuwei Dihuang pills (LWP), a classical TCM formula, with the function of nourishing kidney yin, has been used for treating Xiao Ke disease in clinic. In this review, we systematically highlighted recent evidence on LWP and T2DM data from clinical and animal studies, summarized the clinical application, pharmacological mechanism and the active compounds of LWP for the treatment of T2DM. This systematic review will provide an insightful understanding of TCM formulas, pharmacological mechanisms, medicinal-disease interactions, and will lay a foundation for the development of new drug therapy for T2DM.Entities:
Keywords: Effective substance; Liuwei Dihuang pills; Pharmacological; Type 2 diabetes; Xiao Ke disease
Mesh:
Substances:
Year: 2019 PMID: 31683180 DOI: 10.1016/j.biopha.2019.109564
Source DB: PubMed Journal: Biomed Pharmacother ISSN: 0753-3322 Impact factor: 6.529