Literature DB >> 31683064

Technical report: xMAPr - High-dynamic-range (HDR) quantification of antigen-specific antibody binding.

Tanja C Meyer1, Frank Schmidt2, Jörn Steinke3, Barbara M Bröker3, Uwe Völker1, Stephan Michalik4.   

Abstract

Here, we demonstrate a high-dynamic-range quantification of antibody binding to single antigens in a multiplexed suspension bead array format. Using a dilution-based approach and the newly developed data analysis tool the quantitative dynamic range is increased by three orders of magnitude in the selected samples. The strong increase in dynamic range results in a more robust data basis for downstream analyses.
Copyright © 2019 Elsevier B.V. All rights reserved.

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Year:  2019        PMID: 31683064     DOI: 10.1016/j.jprot.2019.103577

Source DB:  PubMed          Journal:  J Proteomics        ISSN: 1874-3919            Impact factor:   4.044


  2 in total

1.  Direct imaging of antigen-antibody binding by atomic force microscopy.

Authors:  Jing Hu; Mingyan Gao; Zuobin Wang; Yujuan Chen; Zhengxun Song; Hongmei Xu
Journal:  Appl Nanosci       Date:  2020-09-24       Impact factor: 3.674

2.  Polyvalent Immunoglobulin Preparations Inhibit Pneumolysin-Induced Platelet Destruction.

Authors:  Friederike Wiebe; Stefan Handtke; Jan Wesche; Annabel Schnarre; Raghavendra Palankar; Martina Wolff; Kristin Jahn; Franziska Voß; Sabrina Weißmüller; Jörg Schüttrumpf; Andreas Greinacher; Sven Hammerschmidt
Journal:  Thromb Haemost       Date:  2021-12-16       Impact factor: 6.681

  2 in total

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