| Literature DB >> 31679464 |
Peter Lloyd-Sherlock1, Sutapa Agrawal2, Mary Amoakoh-Coleman3, Selasie Adom4, Ebenezer Adjetey-Sorsey5, Ilaria Rocco6, Nadia Minicuci6.
Abstract
Background: There is limited evidence about the prevalence of depression among older people in sub-Saharan Africa, about access to treatment or the potential efficacy of community-based interventions.Objective: Using nationally representative data from the WHO SAGE survey, we examine the prevalence of and factors associated with depression among people aged 50 and over in Ghana. Compare self-reported diagnosis and a symptom algorithm to assess treatment gaps and factors associated with the size of gap. Assess the feasibility of a small community-based intervention specifically for older people.Method: Prevalence and treatment data were taken from the WHO SAGE 2007 survey in Ghana, including 4,725 people aged 50 or over. Outcomes of interest were self-reported depression and diagnosis of depression derived from a symptom-based algorithm. The data were subjected to bivariate and multivariate analysis. In parallel, a pilot intervention was conducted with 35 older people, which included screening by a trained psychiatrist and follow-up group sessions of psychotherapy.Entities:
Keywords: Africa; Depression; feasibility study; mental health; older adults; prevalence
Mesh:
Year: 2019 PMID: 31679464 PMCID: PMC6844439 DOI: 10.1080/16549716.2019.1678282
Source DB: PubMed Journal: Glob Health Action ISSN: 1654-9880 Impact factor: 2.640
Items included in the WHO SAGE depression diagnostic algorithm.
| During the last 12 months, have you had a period lasting several days when you felt sad, empty or depressed? |
| During the last 12 months, have you had a period lasting several days when you lost interest in most things you usually enjoy such as personal relationships, work or hobbies/recreation? |
| During the last 12 months, have you had a period lasting several days when you have been feeling your energy decreased or that you are tired all the time? |
| Was this period [of sadness/loss of interest/low energy] for more than 2 weeks? |
| Was this period [of sadness/loss of interest/low energy] most of the day, nearly every day? |
| During this period, did you lose your appetite? |
| Did you notice any slowing down in your thinking? |
| Did you notice any problems falling asleep? |
| Did you notice any problems walking up too early? |
| During this period, did you have any difficulties concentrating; for example, listening to others, working, watching TV, listening to the radio? |
| Did you notice any slowing down in your moving around? |
| During this period, did you feel anxious and worried most days? |
| During this period, were you so restless or jittery nearly every day that you paced up and down and couldn’t sit still? |
| During this period, did you feel negative about yourself or like you had lost confidence? |
| Did you frequently feel hopeless-that there was no way to improve things? |
| During this period, did your interest in sex decrease? |
| Did you think of death, or wish you were dead? |
| During this period, did you ever try to end your life? |
Distribution % [n] of characteristics WHO SAGE Ghana, 2007.
| Total sample | Self Reported | Chi-square p- value | Symptom-based | Chi-square p-value | |
|---|---|---|---|---|---|
| Prevalence | 1.6[67] | 9.3[395] | |||
| Age (years) | <0.0001*** | <0.0001***1 | |||
| [50-59] | 1883 | 0.7[11] | 7.0[117] | ||
| [60-69] | 1305 | 1.4[17] | 9.9[118] | ||
| [70-79] | 1071 | 2.5[24] | 10.6[103] | ||
| [80+] | 473 | 3.5[15] | 13.4[57] | ||
| Sex | <0.0001*** | <0.0001*** | |||
| Males | 2379 | 0.9[20] | 7.4[167] | ||
| Females | 2345 | 2.3[47] | 11.3[228] | ||
| Marital status | 0.001** | <0.0001*** | |||
| Never married | 58 | 0.0[0] | 14.0[7] | ||
| Married/Cohabiting | 2739 | 1.0[23] | 7.2[174] | ||
| Separated/Divorced | 624 | 2.8[17] | 11.2[68] | ||
| Widowed | 1276 | 2.3[27] | 12.3[146] | ||
| Education | 0.063* | 0.022* | |||
| None | 2380 | 1.5[35] | 10.3[244] | ||
| Primary | 894 | 2.5[22] | 8.4[75] | ||
| Secondary | 878 | 0.9[8] | 8.3[73] | ||
| Higher | 151 | 1.3[2] | 4.0[6] | ||
| Location | 0.0578 | 0.314 | |||
| Urban | 1927 | 2.0[35] | 9.8[172] | ||
| Rural | 2803 | 1.3[32] | 8.9[226] | ||
| Wealth quintile | 0.343 | 0.019* | |||
| Poorest | 939 | 0.8[7] | 8.0[68] | ||
| Q2 | 940 | 2.0[17] | 12.1[102] | ||
| Q3 | 949 | 1.5[13] | 9.4[80] | ||
| Q4 | 934 | 1.7[15] | 9.3[81] | ||
| Richest | 961 | 1.7[15] | 7.8[67] |
Odds ratio (with 95%CI) of symptom-based depression and diagnosis.
| Characteristics | OR(95%CI) for reporting symptom-based depression | P values | OR (95%CI) for reporting symptoms of depression but not a diagnosis | P values |
|---|---|---|---|---|
| Age in years | ||||
| 50–59 | 1.00 | 1.00 | ||
| 60–69 | 1.28 (0.94–1.73) | 0.115 | 1.23(0.89–1.70 | 0.206 |
| 70–79 | 1.27(0.91–1.74) | 0.155 | 1.08(0.77–1.52) | 0.766 |
| 80+ | 1.96(1.24–3.02) | 0.004 | 1.26(0.79–2.01) | 0.785 |
| Sex | ||||
| Male | 1.00 | 1.00 | ||
| Female | 1. 35(1.01–1.82) | 0.046 | 1.30(0.98–1.72) | 0.068 |
| Educational status | ||||
| None | 1.00 | 1.00 | ||
| Primary | 0.94(0.68–1.31) | 0.733 | 0.83(0.58–1.18) | 0.304 |
| Secondary | 0.89(0.62–1.28) | 0.523 | 0.84(0.57–1.24) | 0.377 |
| Higher | 0.65(0.20–2.09) | 0.26(0.09–0.79) | ||
| Marital Status | ||||
| Never married | 1.00 | 1.00 | ||
| Currently Married/cohabiting | 0.76(0.32–1.83) | 0.547 | 0.64(0.27–1.53) | 0.316 |
| Separated/divorced | 1.08(0.44–2.64) | 0.874 | 0.81(0.33–1.99) | 0.644 |
| Widowed | 1.08(0.44–2.63) | 0.869 | 0.94(0.39–2.27) | 0.884 |
| Location | ||||
| Urban | 1.00 | 1.00 | ||
| Rural | 0.86(0.66–1.12) | 0.275 | 0.81(0.61–1.07) | 0.644 |
| Wealth quintile | ||||
| Poorest | 1.00 | 1.00 | ||
| Q2 | 1.51(1.04–2.19) | 0.027 | 1.22(0.84–1.75) | 0.291 |
| Q3 | 1.25(0.86–1.82) | 0.246 | 1.15(0.78–1.70) | 0.482 |
| Q4 | 1.40(0.95–2.07) | 0.087 | 1.19(0.79–1.80) | 0.397 |
| Richest | 1.21(0.76–1.93) | 0.423 | 1.20(0.75–1.93) | 0.453 |
SAGE respondents reporting diagnosis and treatment of depression.
| Diagnosed | Treated in last 2 weeks (% of diagnosed and n) | Treated in last 2 weeks but reporting symptoms (n) | Treated in last 12 months (% of diagnosed and n) | Treated in last 12 months but reporting symptoms (n) | |
|---|---|---|---|---|---|
| Male | 0.8[20] | 25.0[5] | 29.4[5] | 50.0[10] | 58.8[10] |
| Female | 2.3[47] | 19.2[9] | 24.2[8] | 36.2[17] | 51.5[17] |
| Urban | 2.0[35] | 20.0[7] | 30.4[7] | 37.1[13] | 56.5[13] |
| Rural | 1.3[32] | 21.9[7] | 22.2[6] | 43.8[14] | 51.9[14] |
| Total | 67 | 20.9[14] | 13 | 40.3[27] | 27 |
Selected characteristics of study participants.
| 60–69 years old | 70–79 years old | 80+ years old | ||
|---|---|---|---|---|
| Sex | Male | 3 | 6 | 3 |
| Female | 10 | 7 | 6 | |
| Marital status | Single | 0 | 3 | 0 |
| Married | 4 | 2 | 3 | |
| Separated | 1 | 3 | 1 | |
| Widowed | 8 | 5 | 5 | |
| Pension | Yes | 6 | 10 | 5 |
| No | 7 | 3 | 4 | |
| Total | 13 | 13 | 9 |
Comparison of depression evaluations from SAGE and psychiatric evaluation.
| N | % | |
|---|---|---|
| Not Depressed (Both) | 20 | 57.1 |
| Depressed SAGE/Not Depressed Psyc | 5 | 14.3 |
| Not Depressed SAGE/Depressed Psyc | 0 | 0.0 |
| Depressed (Both) | 10 | 28.6 |
| Agreement | 30 | 85.7 |
| Discordant | 5 | 14.3 |
| Total | 35 | |
| Sensitivity of SAGE tool | 10/10 = 100.0% | |
| Specificity of SAGE tool | 20/25 = 80.0% |