Literature DB >> 31678571

Long noncoding RNA TP73-AS1 in human cancers.

Feihu Chu1, Lusha Xue2, Haiyan Miao3.   

Abstract

Long noncoding RNAs (lncRNAs) play an important role in tumor development. With the development of sequencing technology, many new lncRNAs have been discovered. lncRNA TP73-AS1 is abnormally expressed in many cancers. A summary of the current literature related to TP73-AS1 reveals that TP73-AS1 mainly regulates the occurrence and development of tumors through the mechanism of competitive endogenous RNA (ceRNA). In addition, the abnormal expression of TP73-AS1 can regulate the malignant function of tumor cells through a variety of possible mechanisms. All evidence suggests that TP73-AS1 may be a potential diagnostic biomarker or a new cancer therapeutic target.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biomarker; Cancer; Long noncoding RNA; TP73-AS1; ceRNA

Mesh：

Substances：

Year:  2019        PMID： 31678571     DOI： 10.1016/j.cca.2019.09.024

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  6 in total

1.  LncRNA POT1-AS1 accelerates the progression of gastric cancer by serving as a competing endogenous RNA of microRNA-497-5p to increase PDK3 expression.

Authors:  Wei-Min Chen; Yi-Ming Chen; Si-Yuan Jiang; Yuan-Ping Tao; Yong-Gang Hong; Le Yang; Hao Zheng; Jian-Qing Chen
Journal:  J Gastrointest Oncol       Date:  2021-12

2.  Long non-coding RNA GAS6-AS1 enhances breast cancer cell aggressiveness by functioning as a competing endogenous RNA of microRNA-215-5p to enhance SOX9 expression.

Authors:  Xiu-Ping Wu; Zhi-Qiang Xu; Wang-Mei Xie; Yao-Long Lai; Kai He; Yan Jiang; Zhen-Chao Xu; Yi-Na Lin; Yuan-Fu Xie
Journal:  Exp Ther Med       Date:  2021-12-02       Impact factor: 2.447

3.  Long noncoding RNA LINC00520 accelerates the progression of colorectal cancer by serving as a competing endogenous RNA of microRNA-577 to increase HSP27 expression.

Authors:  Xi-Han Jin; Yong-Gang Hong; Peng Li; Li-Qiang Hao; Ming Chen
Journal:  Hum Cell       Date:  2020-03-07       Impact factor: 4.174

4.  LncRNA TP73-AS1 Exacerbates the Non-Small-Cell Lung Cancer (NSCLC) Process via Regulating miR-125a-3p-Mediated ACTN4.

Authors:  Yueyang Tong; Zhemin Feng; Yaqian Li; Chenxi Yan; Wenbo He; Xueyuan Chen
Journal:  Evid Based Complement Alternat Med       Date:  2022-09-09       Impact factor: 2.650

5.  LncRNA-ENST00000543604 exerts a tumor-promoting effect via miRNA 564/AEG-1 or ZNF326/EMT and predicts the prognosis of and chemotherapeutic effect in colorectal cancer.

Authors:  Weimin Wang; Zhen Zhou; Xiaojun Dai; Haibo Wang; Jun Jin; Ke Min; Yunfan Wang; Mengying Lv; Yanqing Liu; Yan Zhou
Journal:  Front Oncol       Date:  2022-08-23       Impact factor: 5.738

6.  Evaluate the immune-related eRNA models and signature score to predict the response to immunotherapy in thyroid carcinoma.

Authors:  Pu Wu; Jinyuan Shi; Zhiyuan Wang; Wei Sun; Hao Zhang
Journal:  Cancer Cell Int       Date:  2022-10-10       Impact factor: 6.429
  6 in total

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