Literature DB >> 316773

The role of the left end of the H-2b haplotype in the male-specific cytotoxic T cell response.

H von Boehmer, K Turton, W Haas.   

Abstract

The male-specific cytotoxic T cell response was tested in various mouse strains. We found that priming with 10(7) nonirradiated or 2 x 10(7) X-irradiated cells (2000 Rad) was similarly effective in B6 mice. We have avoided possible allogeneic effects due to priming F1 hybrids with parental cells and tested all mice after the same time interval for generation of male-specific cytotoxic T lymphocytes in vitro. Under these conditions, we found an absolute requirement for H-2b gene products, encoded left of B, in order to see male-specific responses.

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Year:  1979        PMID： 316773     DOI： 10.1002/eji.1830091115

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  10 in total

1.  Unsuitability of the assay for cell-mediated lympholysis in inbred mice for H-Y antigen determination of human cells.

Authors:  A Braun; H Cleve
Journal:  Hum Genet       Date:  1987-08       Impact factor: 4.132

2.  Cytotoxic T-cell response to H-Y antigen by B6.C-H-2bm12 and B10.BR mice.

Authors:  A Juretić; E Juretić; Z A Nagy; J Klein
Journal:  Immunology       Date:  1985-08       Impact factor: 7.397

3.  Analysis of haplotype preference in the cytotoxic T-cell response to H-Y.

Authors:  M Brenan; E Simpson; A Müllbacher
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

4.  Sex-specific T-cell regulation of angiotensin II-dependent hypertension.

Authors:  Hong Ji; Wei Zheng; Xiangjun Li; Jun Liu; Xie Wu; Monan Angela Zhang; Jason G Umans; Meredith Hay; Robert C Speth; Shannon E Dunn; Kathryn Sandberg
Journal:  Hypertension       Date:  2014-06-16       Impact factor: 10.190

5.  Cell-mediated cytotoxicity to non-MHC alloantigens on mouse epidermal cells. VI. Influence of the MHC on the tissue specificity of cytotoxic T-lymphocyte responses.

Authors:  J D Tyler; W J Burlingham; C S David; D Steinmuller
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

6.  Non-H-2 and H-2-linked immune response genes control the cytotoxic T-cell response to H-Y.

Authors:  W Fierz; M Brenan; A Müllbacher; E Simpson
Journal:  Immunogenetics       Date:  1982-03       Impact factor: 2.846

7.  Early development of the T cell repertoire. In vivo treatment of neonatal mice with anti-Ia antibodies interferes with differentiation of I-restricted T cells but not K/D-restricted T cells.

Authors:  A M Kruisbeek; M J Fultz; S O Sharrow; A Singer; J J Mond
Journal:  J Exp Med       Date:  1983-06-01       Impact factor: 14.307

8.  The cytotoxic T cell response to the male-specific histocompatibility antigen (H-Y) is controlled by two dominant immune response genes, one in the MHC, the other in the Tar alpha-locus.

Authors:  R Epstein; G Sham; J Womack; J Yagüe; E Palmer; M Cohn
Journal:  J Exp Med       Date:  1986-04-01       Impact factor: 14.307

9.  Analysis of H-2 determinants recognized during the induction of H-Y-immune cytotoxic T cells by monoclonal antibodies in vitro.

Authors:  M Brenan; A Müllbacher
Journal:  J Exp Med       Date:  1981-08-01       Impact factor: 14.307

10.  Presentation of the H-Y antigen on Langerhans' cell-negative corneal grafts downregulates the cytotoxic T cell response and converts responder strain mice into phenotypic nonresponders.

Authors:  J S Peeler; D G Callanan; M W Luckenbach; J Y Niederkorn
Journal:  J Exp Med       Date:  1988-11-01       Impact factor: 14.307
  10 in total

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