Literature DB >> 31677018

Dose limits for occupational exposure to ionising radiation and genotoxic carcinogens: a German perspective.

Werner Rühm1, Joachim Breckow2, Günter Dietze3, Anna Friedl4, Rüdiger Greinert5, Peter Jacob6, Stephan Kistinger7, Rolf Michel8, Wolfgang-Ulrich Müller9, Heinz Otten10, Christian Streffer9, Wolfgang Weiss11.   

Abstract

This paper summarises the view of the German Commission on Radiological Protection ("Strahlenschutzkommission", SSK) on the rationale behind the currently valid dose limits and dose constraints for workers recommended by the International Commission on Radiological Protection (ICRP). The paper includes a discussion of the reasoning behind current dose limits followed by a discussion of the detriment used by ICRP as a measure for stochastic health effects. Studies on radiation-induced cancer are reviewed because this endpoint represents the most important contribution to detriment. Recent findings on radiation-induced circulatory disease that are currently not included in detriment calculation are also reviewed. It appeared that for detriment calculations the contribution of circulatory diseases plays only a secondary role, although the uncertainties involved in their risk estimates are considerable. These discussions are complemented by a review of the procedures currently in use in Germany, or in discussion elsewhere, to define limits for genotoxic carcinogens. To put these concepts in perspective, actual occupational radiation exposures are exemplified with data from Germany, for the year 2012, and regulations in Germany are compared to the recommendations issued by ICRP. Conclusions include, among others, considerations on radiation protection concepts currently in use and recommendations of the SSK on the limitation of annual effective dose and effective dose cumulated over a whole working life.

Entities:  

Keywords:  Dose limits; Genotoxic carcinogens; Ionising radiation; Radiation protection

Year:  2019        PMID: 31677018     DOI: 10.1007/s00411-019-00817-x

Source DB:  PubMed          Journal:  Radiat Environ Biophys        ISSN: 0301-634X            Impact factor:   1.925


  66 in total

1.  Background radiation and childhood leukemia: A nationwide register-based case-control study.

Authors:  Atte Nikkilä; Sini Erme; Hannu Arvela; Olli Holmgren; Jani Raitanen; Olli Lohi; Anssi Auvinen
Journal:  Int J Cancer       Date:  2016-07-22       Impact factor: 7.396

2.  Three loci in Escherichia coli K-12 that control the excision of pyrimidine dimers and certain other mutagen products from DNA.

Authors:  P Howard-Flanders; R P Boyce; L Theriot
Journal:  Genetics       Date:  1966-06       Impact factor: 4.562

Review 3.  Quantitative bases for developing a unified index of harm.

Authors: 
Journal:  Ann ICRP       Date:  1985

4.  The relationship between the rate of DNA synthesis and its inhibition by ultraviolet light in mammalian cells.

Authors:  J E Cleaver
Journal:  Radiat Res       Date:  1967-04       Impact factor: 2.841

5.  Studies of the mortality of atomic bomb survivors, Report 14, 1950-2003: an overview of cancer and noncancer diseases.

Authors:  Kotaro Ozasa; Yukiko Shimizu; Akihiko Suyama; Fumiyoshi Kasagi; Midori Soda; Eric J Grant; Ritsu Sakata; Hiromi Sugiyama; Kazunori Kodama
Journal:  Radiat Res       Date:  2011-12-15       Impact factor: 2.841

6.  The concept of the effective dose--a proposal for the combination of organ doses.

Authors:  W Jacobi
Journal:  Radiat Environ Biophys       Date:  1975-06-18       Impact factor: 1.925

7.  Solid cancer mortality in the techa river cohort (1950-2007).

Authors:  S J Schonfeld; L Y Krestinina; S Epifanova; M O Degteva; A V Akleyev; D L Preston
Journal:  Radiat Res       Date:  2013-01-04       Impact factor: 2.841

8.  Mortality from diseases other than cancer following low doses of ionizing radiation: results from the 15-Country Study of nuclear industry workers.

Authors:  M Vrijheid; E Cardis; P Ashmore; A Auvinen; J-M Bae; H Engels; E Gilbert; G Gulis; Rr Habib; G Howe; J Kurtinaitis; H Malker; Cr Muirhead; Db Richardson; F Rodriguez-Artalejo; A Rogel; M Schubauer-Berigan; H Tardy; M Telle-Lamberton; M Usel; K Veress
Journal:  Int J Epidemiol       Date:  2007-07-31       Impact factor: 7.196

9.  A prospective follow-up study of the association of radiation exposure with fatal and non-fatal stroke among atomic bomb survivors in Hiroshima and Nagasaki (1980-2003).

Authors:  Ikuno Takahashi; Robert D Abbott; Tomohiko Ohshita; Tetsuya Takahashi; Kotaro Ozasa; Masazumi Akahoshi; Saeko Fujiwara; Kazunori Kodama; Masayasu Matsumoto
Journal:  BMJ Open       Date:  2012-02-03       Impact factor: 2.692

10.  Radiation exposure and circulatory disease risk: Hiroshima and Nagasaki atomic bomb survivor data, 1950-2003.

Authors:  Yukiko Shimizu; Kazunori Kodama; Nobuo Nishi; Fumiyoshi Kasagi; Akihiko Suyama; Midori Soda; Eric J Grant; Hiromi Sugiyama; Ritsu Sakata; Hiroko Moriwaki; Mikiko Hayashi; Manami Konda; Roy E Shore
Journal:  BMJ       Date:  2010-01-14
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  1 in total

1.  Do we really need the "detriment" for radiation protection?

Authors:  Joachim Breckow
Journal:  Radiat Environ Biophys       Date:  2020-06-24       Impact factor: 1.925

  1 in total

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