Literature DB >> 31676269

A Wish List for Drug Development in Pediatrics.

Rachel Meyers1.   

Abstract

This commentary illustrates and summarizes some of the many issues with dosage forms and drug delivery that arise in everyday practice for clinicians caring for pediatric patients. While advances in drug development for children and expansion of labeling information in this age group have made great strides in improving care, there is much to be desired in the area of dosage forms. From liquids that are unpalatable to the need for extemporaneous compounding of parenteral doses in syringes that are meant for immediate use but used to store medications for hours to weeks, the list of challenges is long. Many of these problems exist for drugs which have long been generic, but some problems have arisen from new drugs as well. Pediatric clinicians and dosage form developers should work together to create solutions.
Copyright © 2020 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  excipient(s); formulation; oral drug delivery; parenteral drug delivery; pediatric

Mesh:

Substances:

Year:  2019        PMID: 31676269     DOI: 10.1016/j.xphs.2019.10.029

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  A Pediatrics Utilization Study in The Netherlands to Identify Active Pharmaceutical Ingredients Suitable for Inkjet Printing on Orodispersible Films.

Authors:  J Carolina Visser; Lisa Wibier; Olga Kiefer; Mine Orlu; Jörg Breitkreutz; Herman J Woerdenbag; Katja Taxis
Journal:  Pharmaceutics       Date:  2020-02-17       Impact factor: 6.321

2.  The best pharmaceuticals for children-what can we do?

Authors:  Hao Li; Fang-Hong Shi; Shi-Ying Huang; Shun-Guo Zhang; Hui-Wen Chen
Journal:  Transl Pediatr       Date:  2020-04
  2 in total

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