| Literature DB >> 31675492 |
Saiyu Hang1, Jun R Huh2.
Abstract
How does stress promote anxiety? In this issue of Cell, Fan et al. report that immune cells have a direct role in this process. They show that chronic stress promotes mitochondrial fission in CD4+ T cells, causing increased synthesis of xanthine, which acts on the brain and induces anxiety-like behaviors.Entities:
Mesh：
Year: 2019 PMID： 31675492 DOI： 10.1016/j.cell.2019.10.012
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582