Literature DB >> 31673524

Current landscape of palliative radiotherapy for non-small-cell lung cancer.

Raphael Jumeau1, Florent Vilotte1, André-Dante Durham1, Esat-Mahmut Ozsahin1.   

Abstract

Radiotherapy (RT) is a cornerstone in the management of advanced stage III and stage IV non-small-cell lung cancer (NSCLC) patients. Despite international guidelines, clinical practice remains heterogeneous. Additionally, the advent of stereotactic ablative RT (SABR) and new systemic treatments such as immunotherapy have shaken up dogmas in the approach of these patients. This review will focus on palliative thoracic RT for NSCLC but will also discuss the role of stereotactic radiotherapy, endobronchial brachytherapy (EBB), the interest of concomitant treatments (chemotherapy and immunotherapy), and the role of RT in lung cancer emergencies with palliative intent. 2019 Translational Lung Cancer Research. All rights reserved.

Entities:  

Keywords:  Lung cancer; palliative intent; radiotherapy

Year:  2019        PMID： 31673524      PMCID： PMC6795576          DOI： 10.21037/tlcr.2019.08.10

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN： 2218-6751


  73 in total

1.  Palliative thoracic radiation therapy for non-small cell lung cancer: 2018 Update of an American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline.

Authors:  Benjamin Moeller; Ehsan H Balagamwala; Aileen Chen; Kimberly M Creach; Giuseppe Giaccone; Matthew Koshy; Sandra Zaky; George Rodrigues
Journal:  Pract Radiat Oncol       Date:  2018-04-04

Review 2.  Bleeding in cancer patients and its treatment: a review.

Authors:  Candice Johnstone; Shayna E Rich
Journal:  Ann Palliat Med       Date:  2017-12-18

3.  Results of the Dutch National study of the palliative effect of irradiation using two different treatment schemes for non-small-cell lung cancer.

Authors:  Gijsbert W P M Kramer; Stofferinus L Wanders; Ed M Noordijk; Ernest J A Vonk; Hans C van Houwelingen; Wilbert B van den Hout; Ronald B Geskus; Mirjam Scholten; Jan-Willem H Leer
Journal:  J Clin Oncol       Date:  2005-05-01       Impact factor: 44.544

4.  Laser augmented by brachytherapy versus laser alone in the palliation of adenocarcinoma of the oesophagus and cardia: a randomised study.

Authors:  G M Spencer; S M Thorpe; G M Blackman; J Solano; J S Tobias; L B Lovat; S G Bown
Journal:  Gut       Date:  2002-02       Impact factor: 23.059

5.  Split-course palliative radiotherapy for advanced non-small cell lung cancer.

Authors:  Su K Metcalfe; Michael T Milano; Kevin Bylund; Therese Smudzin; Philip Rubin; Yuhchyau Chen
Journal:  J Thorac Oncol       Date:  2010-02       Impact factor: 15.609

6.  Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer.

Authors:  Scott J Antonia; Augusto Villegas; Davey Daniel; David Vicente; Shuji Murakami; Rina Hui; Takashi Yokoi; Alberto Chiappori; Ki H Lee; Maike de Wit; Byoung C Cho; Maryam Bourhaba; Xavier Quantin; Takaaki Tokito; Tarek Mekhail; David Planchard; Young-Chul Kim; Christos S Karapetis; Sandrine Hiret; Gyula Ostoros; Kaoru Kubota; Jhanelle E Gray; Luis Paz-Ares; Javier de Castro Carpeño; Catherine Wadsworth; Giovanni Melillo; Haiyi Jiang; Yifan Huang; Phillip A Dennis; Mustafa Özgüroğlu
Journal:  N Engl J Med       Date:  2017-09-08       Impact factor: 91.245

Review 7.  Lung cancer. Palliative care.

Authors:  Paul A Kvale; Michael Simoff; Udaya B S Prakash
Journal:  Chest       Date:  2003-01       Impact factor: 9.410

8.  Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA).

Authors:  Paul W Sperduto; T Jonathan Yang; Kathryn Beal; Hubert Pan; Paul D Brown; Ananta Bangdiwala; Ryan Shanley; Norman Yeh; Laurie E Gaspar; Steve Braunstein; Penny Sneed; John Boyle; John P Kirkpatrick; Kimberley S Mak; Helen A Shih; Alex Engelman; David Roberge; Nils D Arvold; Brian Alexander; Mark M Awad; Joseph Contessa; Veronica Chiang; John Hardie; Daniel Ma; Emil Lou; William Sperduto; Minesh P Mehta
Journal:  JAMA Oncol       Date:  2017-06-01       Impact factor: 31.777

9.  Intentional avoidance of the esophagus using intensity modulated radiation therapy to reduce dysphagia after palliative thoracic radiation.

Authors:  Patrick V Granton; David A Palma; Alexander V Louie
Journal:  Radiat Oncol       Date:  2017-01-26       Impact factor: 3.481

10.  Lung cancer prognostic index: a risk score to predict overall survival after the diagnosis of non-small-cell lung cancer.

Authors:  Marliese Alexander; Rory Wolfe; David Ball; Matthew Conron; Robert G Stirling; Benjamin Solomon; Michael MacManus; Ann Officer; Sameer Karnam; Kate Burbury; Sue M Evans
Journal:  Br J Cancer       Date:  2017-07-20       Impact factor: 7.640
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  11 in total

1.  Factors affecting survival after palliative radiotherapy in patients with lung cancer.

Authors:  Fátima Aires; Edna Rodrigues; Margarida Marques; Maria Pinto
Journal:  Rep Pract Oncol Radiother       Date:  2021-09-30

2.  Clinical efficacy and safety of Huachansu injection combination with platinum-based chemotherapy for advanced non-small cell lung cancer: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Xinmei Tan; Xueyan Liang; Jiaxi Xi; Sitong Guo; Mingyu Meng; Xiaoyu Chen; Yan Li
Journal:  Medicine (Baltimore)       Date:  2021-09-10       Impact factor: 1.817

3.  p70S6K Promotes Acquired Resistance of Erlotinib Through Induction of Epithelial-Mesenchymal Transition in Non-Small Cell Lung Carcinoma.

Authors:  Min Li; Hongling Chen; Tong Sun; Zhuo Ma; Xi Chen; Dandan Wu; Wenbin Huang; Xuerong Wang
Journal:  Onco Targets Ther       Date:  2020-06-09       Impact factor: 4.147

4.  Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.

Authors:  Jing Li; Dong-Ming Wu; Rong Han; Ye Yu; Shi-Hua Deng; Teng Liu; Ting Zhang; Ying Xu
Journal:  Onco Targets Ther       Date:  2020-04-29       Impact factor: 4.147

5.  Dehydroeffusol inhibits hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer cells through the inactivation of Wnt/β-catenin pathway.

Authors:  Haitao Wei; Feng Zhang; Jiali Wang; Min Zhao; Tao Hou; Li Li
Journal:  Biosci Rep       Date:  2020-05-29       Impact factor: 3.840

Review 6.  A narrative review of evolving roles of radiotherapy in advanced non-small cell lung cancer: from palliative care to active player.

Authors:  Yue Zhou; Fan Yu; Yang Zhao; Ya Zeng; Xi Yang; Li Chu; Xiao Chu; Yida Li; Liqing Zou; Tiantian Guo; Zhengfei Zhu; Jianjiao Ni
Journal:  Transl Lung Cancer Res       Date:  2020-12

Review 7.  Current status and future directions in unresectable stage III non-small cell lung cancer.

Authors:  Esperanza Arriola Arellano; Verónica Díaz Díaz; Joaquín José Cabrera Rodríguez
Journal:  J Clin Transl Res       Date:  2020-10-29

8.  Treatment and Survival in Advanced Non-Small Cell Lung Cancer, Urothelial, Ovarian, Gastric and Kidney Cancer: A Nationwide Comprehensive Evaluation.

Authors:  Signe Sørup; Bianka Darvalics; Azza Ahmed Khalil; Marianne Nordsmark; Mette Hæe; Frede Donskov; Mads Agerbæk; Leo Russo; Dina Oksen; Emmanuelle Boutmy; Patrice Verpillat; Deirdre Cronin-Fenton
Journal:  Clin Epidemiol       Date:  2021-09-22       Impact factor: 4.790

9.  Optimal Initial Time Point of Local Radiotherapy for Unresectable Lung Adenocarcinoma: A Retrospective Analysis on Overall Arrangement of Local Radiotherapy in Advanced Lung Adenocarcinoma.

Authors:  Xinge Li; Jie Wang; Xu Chang; Zhenhua Gao; Feifei Teng; Xue Meng; Jinming Yu
Journal:  Front Oncol       Date:  2022-02-10       Impact factor: 6.244

Review 10.  Image guidance in radiation therapy for better cure of cancer.

Authors:  Vincent Grégoire; Matthias Guckenberger; Karin Haustermans; Jan J W Lagendijk; Cynthia Ménard; Richard Pötter; Ben J Slotman; Kari Tanderup; Daniela Thorwarth; Marcel van Herk; Daniel Zips
Journal:  Mol Oncol       Date:  2020-06-29       Impact factor: 6.603
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