| Literature DB >> 31673464 |
Ahmet Yontem1, Nagehan Aslan1, Ozden Ozgur Horoz1, Aysun Karabay Beyazit2, Engin Melek2, Dincer Yildizdas1.
Abstract
Metformin is an oral antidiabetic medication which belongs to the class biguanide. Its most hazardous and life-threatening side effect is lactic acidosis which has been increasingly reported in recent years. Early diagnosis and aggressive treatment approaches have significantly reduced morbidity and mortality rates in metformin intoxication. In this case report, we emphasize the importance of early continuous renal replacement therapy in metformin-associated lactic acidosis in a 16-year-old patient who developed severe renal damage during the follow-up period of renal replacement therapy due to lactic acidosis after taking metformin in a suicide attempt. © Thieme Medical Publishers.Entities:
Keywords: lactic acidosis; metformin; overdose; renal replacement therapy
Year: 2019 PMID: 31673464 PMCID: PMC6821537 DOI: 10.1055/s-0039-1695046
Source DB: PubMed Journal: J Pediatr Intensive Care ISSN: 2146-4626