Literature DB >> 31671168

Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents.

Sheryl M Southard, Rama P Kotipatruni, William L Rust.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0203126.].

Entities:  

Year:  2019        PMID: 31671168      PMCID: PMC6822754          DOI: 10.1371/journal.pone.0224944

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


There are a number of errors in Fig 3, “Characterization of SR1423,” panels B-C. Please see the complete, correct Fig 3 here.
Fig 3

Characterization of SR1423.

SR1423 cells have characteristics typical of pluripotent stem cells. (A) In the undifferentiated state, SR1423 expressed the markers of pluripotent stem cells Oct4, Tra-1-81, Tra-1-60, Sox2, and SSEA4. Images include nuclear stain (blue). (B) Cell karyotype after 40 passages in culture. Cells were karyotyped at passage 11 and passage 40 with identical results. (C) DNA fingerprint of SR1423 as assessed by single tandem repeat analysis (STR). (D) Column mean and error bar graph represents SR1423 cell doubling time. Scale bar 100 μm.

Characterization of SR1423.

SR1423 cells have characteristics typical of pluripotent stem cells. (A) In the undifferentiated state, SR1423 expressed the markers of pluripotent stem cells Oct4, Tra-1-81, Tra-1-60, Sox2, and SSEA4. Images include nuclear stain (blue). (B) Cell karyotype after 40 passages in culture. Cells were karyotyped at passage 11 and passage 40 with identical results. (C) DNA fingerprint of SR1423 as assessed by single tandem repeat analysis (STR). (D) Column mean and error bar graph represents SR1423 cell doubling time. Scale bar 100 μm.
  1 in total

1.  Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents.

Authors:  Sheryl M Southard; Rama P Kotipatruni; William L Rust
Journal:  PLoS One       Date:  2018-09-05       Impact factor: 3.240

  1 in total

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