Literature DB >> 31669789

A prospective observational study of heroin users in Johannesburg, South Africa: Assessing psychiatric comorbidities and treatment outcomes.

Nirvana Morgan1, William Daniels2, Ugasvaree Subramaney3.   

Abstract

BACKGROUND: Despite the rise in heroin use in sub Saharan-Africa opioid agonist maintenance treatment (OAMT) is still not state-funded in South Africa and many other African countries. In South Africa there has been little data published on the profile of heroin users and the outcomes of treatment for those who attend public treatment services.
METHODS: 300 heroin users from two state-funded rehabilitation centres in Johannesburg were studied at entry into rehabilitation and 3-months after treatment. Treatment consisted of inpatient detoxification and inpatient psychosocial rehabilitation. Structured interviews measured changes in drug use, psychopathology and criminality post rehabilitation.
RESULTS: Most (65.7%) smoked heroin in combination with cannabis while 29.7% were injecting users. Almost half the sample (49.3%) had at least one mental illness. Of the 252 (84%) participants seen at 3-month follow-up, 6.3% were abstinent of all substances (excluding tobacco), 65.5% had continued heroin use (CHU) and the balance used other substances. At follow-up there were significant decreases in heroin use (p<0.0001) and criminality (p<0.0001). There were however significant increases in alcohol use (p<0.0001), crystalmetamphetamine use (p=0.032) and the prevalence of current episode of major depression (p<0.0001). Just 11.9% received formal psychosocial treatment after leaving rehabilitation. None were on OAMT and only three participants were on psychotropic medication. None were tested for Hepatitis C during the study period and the majority (53%) did not know their HIV status.
CONCLUSION: There are significant gaps in current treatment services for heroin users in South Africa. Retention in treatment and assessment and management of psychiatric and non-psychiatric comorbidities is low. Services need to be more integrated and should also include the provision of OAMT.
Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Comorbidities; Heroin; Heroin dependence; Nyaope; Treatment outcomes

Mesh:

Year:  2019        PMID: 31669789     DOI: 10.1016/j.comppsych.2019.152137

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN: 0010-440X            Impact factor:   3.735


  6 in total

1.  Mental Disorders Are Associated With Leukocytes Telomere Shortening Among People Who Inject Drugs.

Authors:  Mélusine Durand; Nicolas Nagot; Laurent Michel; Sao Mai Le; Huong Thi Duong; Roselyne Vallo; Amélie Vizeneux; Delphine Rapoud; Hoang Thi Giang; Catherine Quillet; Nham Thi Tuyet Thanh; Khuat Thi Hai Oanh; Vu Hai Vinh; Jonathan Feelemyer; Philippe Vande Perre; Khue Pham Minh; Didier Laureillard; Don Des Jarlais; Jean-Pierre Molès
Journal:  Front Psychiatry       Date:  2022-06-17       Impact factor: 5.435

2.  Longitudinal Patterns of Suicidality Among Heroin Users in Johannesburg, South Africa: A Need for Suicide Screening and Intervention.

Authors:  Nirvana Morgan; Ellen-Ge Denton; Ugasvaree Subramaney; William Daniels; Tilman Steinert
Journal:  Front Psychiatry       Date:  2022-05-31       Impact factor: 5.435

3.  Smoking heroin with cannabis versus injecting heroin: unexpected impact on treatment outcomes.

Authors:  Nirvana Morgan; William Daniels; Ugasvaree Subramaney
Journal:  Harm Reduct J       Date:  2019-12-05

4.  An Inverse Relationship Between Alcohol and Heroin Use in Heroin Users Post Detoxification.

Authors:  Nirvana Morgan; William Daniels; Ugasvaree Subramaney
Journal:  Subst Abuse Rehabil       Date:  2020-01-08

5.  The prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in Nairobi, Kenya.

Authors:  Elizabeth Wambui Ngarachu; Sarah Kanana Kiburi; Frederick R Owiti; Rachel Kangethe
Journal:  Subst Abuse Treat Prev Policy       Date:  2022-02-15

6.  Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa.

Authors:  Andrew Scheibe; Shaun Shelly; Tara Gerardy; Zara von Homeyer; Andrea Schneider; Kalvanya Padayachee; Shalon Balaguru Naidoo; Klaas Mtshweni; Ayanda Matau; Harry Hausler; Monique Marks
Journal:  Addict Sci Clin Pract       Date:  2020-02-21
  6 in total

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