Clinical and psychosocial factors can influence the quality of life (QoL) of patients with epilepsy (PWE). OBJECTIVE: The aim of this study was to investigate the association between the Resilience Scale (RS) and the QOLIE-31 (Quality of Life in Epilepsy Inventory), Neurological Disorders Depression Inventory for Epilepsy, and clinical aspects of 137 PWE, at a significance level of p < 0.05. RESULTS: Seizure control, normal EEG (electroencephalographic) background activity, and antiepileptic drug (AED) monotherapy were associated with greater resilience. There was a correlation between resilience and depressive episodes (Pearson correlation: -0.462; p < 0.000) and performance in the MMSE (Mini-Mental State Examination) (0.221, p = 0.015). Improved QoL was associated with greater resilience, self-sufficiency, equanimity, and perseverance. Greater resilience was significantly related to the absence of depressive symptoms (p = 0.001), normal EEG background activity (p = 0.024), and AED monotherapy (p = 0.049) in the linear regression model. CONCLUSION: Clinical, cognitive, and EEG aspects were related to resilience. Depressive symptoms correlate negatively with resilience. Individuals with greater resilience perceive better QoL.
Clinical and psychosocial factors can influence the quality of life (QoL) of patients with epilepsy (PWE). OBJECTIVE: The aim of this study was to investigate the association between the Resilience Scale (RS) and the QOLIE-31 (Quality of Life in Epilepsy Inventory), Neurological Disorders Depression Inventory for Epilepsy, and clinical aspects of 137 PWE, at a significance level of p < 0.05. RESULTS:Seizure control, normal EEG (electroencephalographic) background activity, and antiepileptic drug (AED) monotherapy were associated with greater resilience. There was a correlation between resilience and depressive episodes (Pearson correlation: -0.462; p < 0.000) and performance in the MMSE (Mini-Mental State Examination) (0.221, p = 0.015). Improved QoL was associated with greater resilience, self-sufficiency, equanimity, and perseverance. Greater resilience was significantly related to the absence of depressive symptoms (p = 0.001), normal EEG background activity (p = 0.024), and AED monotherapy (p = 0.049) in the linear regression model. CONCLUSION: Clinical, cognitive, and EEG aspects were related to resilience. Depressive symptoms correlate negatively with resilience. Individuals with greater resilience perceive better QoL.
Authors: Medine I Gulcebi; Emanuele Bartolini; Omay Lee; Christos Panagiotis Lisgaras; Filiz Onat; Janet Mifsud; Pasquale Striano; Annamaria Vezzani; Michael S Hildebrand; Diego Jimenez-Jimenez; Larry Junck; David Lewis-Smith; Ingrid E Scheffer; Roland D Thijs; Sameer M Zuberi; Stephen Blenkinsop; Hayley J Fowler; Aideen Foley; Sanjay M Sisodiya Journal: Epilepsy Behav Date: 2021-02-10 Impact factor: 3.337