Literature DB >> 31668661

Induction of membrane curvature by proteins involved in Golgi trafficking.

Stefanie L Makowski1, Ramya S Kuna1, Seth J Field2.   

Abstract

The Golgi apparatus serves a key role in processing and sorting lipids and proteins for delivery to their final cellular destinations. Vesicle exit from the Golgi initiates with directional deformation of the lipid bilayer to produce a bulge. Several mechanisms have been described by which lipids and proteins can induce directional membrane curvature to promote vesicle budding. Here we review some of the mechanisms implicated in inducing membrane curvature at the Golgi to promote vesicular trafficking to various cellular destinations.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  GOLPH3; Golgi; Membrane curvature; Phosphoinositides; Trafficking; Vesicle budding

Year:  2019        PMID: 31668661      PMCID: PMC7056495          DOI: 10.1016/j.jbior.2019.100661

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN: 2212-4926


  156 in total

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