| Literature DB >> 31668661 |
Stefanie L Makowski1, Ramya S Kuna1, Seth J Field2.
Abstract
The Golgi apparatus serves a key role in processing and sorting lipids and proteins for delivery to their final cellular destinations. Vesicle exit from the Golgi initiates with directional deformation of the lipid bilayer to produce a bulge. Several mechanisms have been described by which lipids and proteins can induce directional membrane curvature to promote vesicle budding. Here we review some of the mechanisms implicated in inducing membrane curvature at the Golgi to promote vesicular trafficking to various cellular destinations.Entities:
Keywords: GOLPH3; Golgi; Membrane curvature; Phosphoinositides; Trafficking; Vesicle budding
Year: 2019 PMID: 31668661 PMCID: PMC7056495 DOI: 10.1016/j.jbior.2019.100661
Source DB: PubMed Journal: Adv Biol Regul ISSN: 2212-4926