Kenneth B Yatai1, Mark J Dunning2, Dennis Wang3. 1. The Medical School, University of Sheffield, Sheffield, UK. 2. Sheffield Bioinformatics Core, University of Sheffield, Sheffield, UK; NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK. 3. NIHR Sheffield Biomedical Research Centre, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK; Department of Computer Science, University of Sheffield, Sheffield, UK. Electronic address: dennis.wang@sheffield.ac.uk.