Jennifer M Ryan1, Jennifer Fortune2, Andrea Stennett2, Cherry Kilbride2, Grace Lavelle2, Wendy Hendrie3, Lorraine DeSouza2, Mohammed Abdul4, Debbie Brewin5, Lee David5, Nana Anokye6, Christina Victor2, Meriel Norris2. 1. Ageing Studies Theme, Institute of Environment, Health and Societies, Brunel University London, London, UK/Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. 2. Ageing Studies Theme, Institute of Environment, Health and Societies, Brunel University London, London, UK. 3. MS Therapy Centre, Norwich, UK. 4. The Berkshire MS Therapy Centre, Reading, UK. 5. Health Economics Theme, Institute of Environment, Health and Societies, Brunel University London, London, UK. 6. 10 Minute CBT, Letchworth Garden City, UK.
Abstract
BACKGROUND: There is limited information regarding the safety, feasibility and acceptability of behaviour-change interventions to increase physical activity (PA) and reduce sedentary behaviour among people with multiple sclerosis (MS). Prior to evaluating efficacy, it is important to identify problems with feasibility and acceptability, which may undermine effectiveness. OBJECTIVE: To examine the safety, feasibility and acceptability of a behaviour-change intervention to increase PA and reduce sedentary behaviour among people with MS. METHODS:Sixty people received a3-month intervention or usual care. Fatigue, pain and adverse events (AEs) were assessed. Feasibility and acceptability were explored through focus groups with physiotherapists and interviews with participants. Fidelity to intervention content, delivery skills, programme receipt and programme task were assessed. RESULTS: There was no difference in AE rate between groups (p = 0.965). Fatigue and pain were not higher in the intervention group at 3 or 9 months. Therapists reported the intervention was feasible to deliver and fidelity was acceptable. Twenty-nine participants (97%) attended at least 75% of sessions. Participants found the intervention acceptable but suggested some amendments were required to intervention components. CONCLUSIONS: The intervention was safe, feasible and acceptable. Although modifications are required to intervention components, the intervention warrants further evaluation in a future trial.
RCT Entities:
BACKGROUND: There is limited information regarding the safety, feasibility and acceptability of behaviour-change interventions to increase physical activity (PA) and reduce sedentary behaviour among people with multiple sclerosis (MS). Prior to evaluating efficacy, it is important to identify problems with feasibility and acceptability, which may undermine effectiveness. OBJECTIVE: To examine the safety, feasibility and acceptability of a behaviour-change intervention to increase PA and reduce sedentary behaviour among people with MS. METHODS: Sixty people received a 3-month intervention or usual care. Fatigue, pain and adverse events (AEs) were assessed. Feasibility and acceptability were explored through focus groups with physiotherapists and interviews with participants. Fidelity to intervention content, delivery skills, programme receipt and programme task were assessed. RESULTS: There was no difference in AE rate between groups (p = 0.965). Fatigue and pain were not higher in the intervention group at 3 or 9 months. Therapists reported the intervention was feasible to deliver and fidelity was acceptable. Twenty-nine participants (97%) attended at least 75% of sessions. Participants found the intervention acceptable but suggested some amendments were required to intervention components. CONCLUSIONS: The intervention was safe, feasible and acceptable. Although modifications are required to intervention components, the intervention warrants further evaluation in a future trial.
Authors: Stephanie L Silveira; Trinh Huynh; Ariel Kidwell; Dena Sadeghi-Bahmani; Robert W Motl Journal: Arch Phys Med Rehabil Date: 2021-02-05 Impact factor: 4.060
Authors: Jennifer Fortune; Meriel Norris; Andrea Stennett; Cherry Kilbride; Grace Lavelle; Wendy Hendrie; Christina Victor; Jennifer Mary Ryan Journal: Sci Rep Date: 2021-10-13 Impact factor: 4.379
Authors: Jennifer Fortune; Meriel Norris; Andrea Stennett; Cherry Kilbride; Grace Lavelle; Wendy Hendrie; Lorraine DeSouza; Christina Victor; Jennifer Mary Ryan Journal: Front Rehabil Sci Date: 2021-12-10