Isabelle Romieu1, Carine Biessy2, Gabriela Torres-Mejía1, Angélica Ángeles-Llerenas1, Gloria Inés Sánchez3, Mauricio Borrero4, Carlos Andrés Ossa5, Carolina Porras6, Ana Cecilia Rodríguez6, Rebecca Ocampo6, María Luisa Garmendia7, Eva Bustamante8, Magali Olivier9, Peggy Porter10, Sabina Rinaldi2. 1. Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico. 2. Section of Nutrition and Metabolism, International Agency for Research on Cancer. Lyon, France. 3. Group Infection and Cancer, School of Medicine, University of Antioquia. Medellín, Colombia. 4. Clínica Vida. Medellín, Colombia. 5. Instituto de Cancerología Las Américas. Medellín, Colombia. 6. Agencia Costarricense de Investigaciones Biomédicas (ACIB)-Fundación INCIENSA. Costa Rica. 7. Instituto de Nutrición y de Tecnología de los Alimentos, Universidad de Chile. Santiago, Chile. 8. Instituto Oncológico Fundación Arturo López Pérez, Providencia. Santiago, Chile. 9. Molecular Mechanisms and Biomarkers Group, Section of Mechanisms of Carcinogenesis, International Agency for Research on Cancer. Lyon, France. 10. Division of Human Biology, Fred Hutchinson Cancer Research Center. Seattle, USA.
Abstract
OBJECTIVE: To describe the rationale and the methodology of a multicenter project to study the etiology of breast cancer in young Latin American women. MATERIALS AND METHODS: The International Agency for Research on Cancer has established an international collaborative population-based case-control study in four countries in Latin America: Chile, Colombia, Costa Rica, and Mexico (the PRECAMA study). Standardized methodologies were developed to collect information on reproductive variables, lifestyle, anthropometry, diet, clinical and pathological data, and biological specimens. The study will be extended to other countries in the region. CONCLUSIONS: PRECAMA is unique in its multidisciplinary approach that combines genetics, genomics, and metabolomics with lifestyle factors. Then data generated through this project will be instrumental to identify major risk factors for molecular subtypes of breast cancer in young women, which will be important for pre- vention and targeted screening programs in Latin America.
OBJECTIVE: To describe the rationale and the methodology of a multicenter project to study the etiology of breast cancer in young Latin American women. MATERIALS AND METHODS: The International Agency for Research on Cancer has established an international collaborative population-based case-control study in four countries in Latin America: Chile, Colombia, Costa Rica, and Mexico (the PRECAMA study). Standardized methodologies were developed to collect information on reproductive variables, lifestyle, anthropometry, diet, clinical and pathological data, and biological specimens. The study will be extended to other countries in the region. CONCLUSIONS: PRECAMA is unique in its multidisciplinary approach that combines genetics, genomics, and metabolomics with lifestyle factors. Then data generated through this project will be instrumental to identify major risk factors for molecular subtypes of breast cancer in young women, which will be important for pre- vention and targeted screening programs in Latin America.
Entities:
Keywords:
Latin America; breast cancer; risk factors; women
Authors: Laura Fejerman; Amelie G Ramirez; Anna María Nápoles; Scarlett Lin Gomez; Mariana C Stern Journal: Cancer Epidemiol Biomarkers Prev Date: 2022-05-04 Impact factor: 4.090