Dmitrii Starkov1,2, Nils Guinand3, Florence Lucieer4, Maurizio Ranieri3, Samuel Cavuscens3, Maksim Pleshkov4,5, Jean-Philippe Guyot3, Herman Kingma4,5, Stefano Ramat6, Angelica Perez-Fornos3, Raymond van de Berg4,5. 1. Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, The Netherlands, dmitrii.n.starkov@gmail.com. 2. Faculty of Physics, Tomsk State Research University, Tomsk, Russian Federation, dmitrii.n.starkov@gmail.com. 3. Service of Otorhinolaryngology Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland. 4. Division of Balance Disorders, Department of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, The Netherlands. 5. Faculty of Physics, Tomsk State Research University, Tomsk, Russian Federation. 6. Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
Abstract
INTRODUCTION: The vestibular implant could become a clinically useful device in the near future. This study investigated the feasibility of restoring the high-frequency dynamic visual acuity (DVA) with a vestibular implant, using the functional Head Impulse Test (fHIT). METHODS: A 72-year-old female, with bilateral vestibulopathy and fitted with a modified cochlear implant incorporating three vestibular electrodes (MED-EL, Innsbruck, Austria), was available for this study. Electrical stimulation was delivered with the electrode close to the lateral ampullary nerve in the left ear. The high-frequency DVA in the horizontal plane was tested with the fHIT. After training, the patient underwent six trials of fHIT, each with a different setting of the vestibular implant: (1) System OFF before stimulation; (2) System ON, baseline stimulation; (3) System ON, reversed stimulation; (4) System ON, positive stimulation; (5) System OFF, without delay after stimulation offset; and (6) System OFF, 25 min delay after stimulation offset. The percentage of correct fHIT scores for right and left head impulses were compared between trials. RESULTS: Vestibular implant stimulation improved the high-frequency DVA compared to no stimulation. This improvement was significant for "System ON, baseline stimulation" (p = 0.02) and "System ON, positive stimulation" (p < 0.001). fHIT scores changed from 19 to 44% (no stimulation) to maximum 75-94% (System ON, positive stimulation). CONCLUSION: The vestibular implant seems capable of improving the high-frequency DVA. This functional benefit of the vestibular implant illustrates again the feasibility of this device for clinical use in the near future.
INTRODUCTION: The vestibular implant could become a clinically useful device in the near future. This study investigated the feasibility of restoring the high-frequency dynamic visual acuity (DVA) with a vestibular implant, using the functional Head Impulse Test (fHIT). METHODS: A 72-year-old female, with bilateral vestibulopathy and fitted with a modified cochlear implant incorporating three vestibular electrodes (MED-EL, Innsbruck, Austria), was available for this study. Electrical stimulation was delivered with the electrode close to the lateral ampullary nerve in the left ear. The high-frequency DVA in the horizontal plane was tested with the fHIT. After training, the patient underwent six trials of fHIT, each with a different setting of the vestibular implant: (1) System OFF before stimulation; (2) System ON, baseline stimulation; (3) System ON, reversed stimulation; (4) System ON, positive stimulation; (5) System OFF, without delay after stimulation offset; and (6) System OFF, 25 min delay after stimulation offset. The percentage of correct fHIT scores for right and left head impulses were compared between trials. RESULTS: Vestibular implant stimulation improved the high-frequency DVA compared to no stimulation. This improvement was significant for "System ON, baseline stimulation" (p = 0.02) and "System ON, positive stimulation" (p < 0.001). fHIT scores changed from 19 to 44% (no stimulation) to maximum 75-94% (System ON, positive stimulation). CONCLUSION: The vestibular implant seems capable of improving the high-frequency DVA. This functional benefit of the vestibular implant illustrates again the feasibility of this device for clinical use in the near future.
Authors: F M P Lucieer; R Van Hecke; L van Stiphout; S Duijn; A Perez-Fornos; N Guinand; V Van Rompaey; H Kingma; M Joore; R van de Berg Journal: J Neurol Date: 2020-10-08 Impact factor: 4.849
Authors: E C Martin; C Leue; P Delespaul; F Peeters; A M L Janssen; R Lousberg; A Erdkamp; S van de Weijer; J Widdershoven; H Blom; T Bruintjes; A Zwergal; E Grill; N Guinand; A Perez-Fornos; M R van de Berg; J J A Stultiens; H Kingma; R van de Berg Journal: J Neurol Date: 2020-07-25 Impact factor: 4.849
Authors: Lisa van Stiphout; Israt Hossein; Merel Kimman; Susan L Whitney; Andrianna Ayiotis; Michael Strupp; Nils Guinand; Angélica Pérez Fornos; Josine Widdershoven; Ángel Ramos-Macías; Vincent Van Rompaey; Raymond van de Berg Journal: Front Neurol Date: 2022-03-17 Impact factor: 4.003
Authors: Raymond van de Berg; Angel Ramos; Vincent van Rompaey; Alexandre Bisdorff; Angelica Perez-Fornos; Jay T Rubinstein; James O Phillips; Michael Strupp; Charles C Della Santina; Nils Guinand Journal: J Vestib Res Date: 2020 Impact factor: 2.354
Authors: D Starkov; M Snelders; F Lucieer; A M L Janssen; M Pleshkov; H Kingma; V van Rompaey; N Herssens; A Hallemans; L Vereeck; C McCrum; K Meijer; N Guinand; A Perez-Fornos; R van de Berg Journal: J Neurol Date: 2020-10-28 Impact factor: 4.849