George W Fryhofer1, Matthew Sloan1, Neil P Sheth2. 1. University of Pennsylvania, Department of Orthopaedic Surgery, 3737 Market Street, Philadelphia, PA, 19104, USA. 2. University of Pennsylvania, Department of Orthopaedic Surgery, 800 Spruce Street, 8th Floor Preston Building, Philadelphia, PA, 19107, USA.
Abstract
INTRODUCTION: Hypoalbuminemia (<3.5 mg/dL) is an accepted marker of malnutrition, but it was unknown if low albumin remained an independent predictor of post-operative complications following primary total hip (THA) and knee (TKA) arthroplasty. METHODS: The National Surgical Quality Improvement Program (NSQIP) database was queried for patients undergoing primary THA and TKA. Propensity score-matched analysis was used to control for co-morbid conditions. RESULTS: Patients with low albumin demonstrated greater odds of death (by 2-21x), morbidity (by 25-51%), re-admission (by 45-54%), and increased length of stay. CONCLUSION: Low albumin remains an independent predictor of adverse outcomes following primary total joint arthroplasty.
INTRODUCTION: Hypoalbuminemia (<3.5 mg/dL) is an accepted marker of malnutrition, but it was unknown if low albumin remained an independent predictor of post-operative complications following primary total hip (THA) and knee (TKA) arthroplasty. METHODS: The National Surgical Quality Improvement Program (NSQIP) database was queried for patients undergoing primary THA and TKA. Propensity score-matched analysis was used to control for co-morbid conditions. RESULTS: Patients with low albumin demonstrated greater odds of death (by 2-21x), morbidity (by 25-51%), re-admission (by 45-54%), and increased length of stay. CONCLUSION: Low albumin remains an independent predictor of adverse outcomes following primary total joint arthroplasty.
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