Literature DB >> 31660009

Challenges of Diabetes Care in Older People With Type 2 Diabetes and the Role of Basal Insulin.

Eugenio Cersosimo1, Pearl G Lee2, Naushira Pandya3.   

Abstract

IN BRIEF The use of long-acting basal insulin analogs is a recommended strategy in older people with diabetes because of their lower risk of hypoglycemia compared to intermediate-acting insulins. In this article, we review the results from recent clinical trials of second-generation basal insulin preparations. We conclude that, although these preparations have improved the management of insulin-requiring older people with type 2 diabetes, there is a need for additional and more specific studies to address the complexities of hyperglycemia management in this population.
© 2019 by the American Diabetes Association.

Entities:  

Year:  2019        PMID: 31660009      PMCID: PMC6794221          DOI: 10.2337/cd18-0074

Source DB:  PubMed          Journal:  Clin Diabetes        ISSN: 0891-8929


  44 in total

1.  Severe hypoglycemia is associated with antidiabetic oral treatment compared with insulin analogs in nursing home patients with type 2 diabetes and dementia: results from the DIMORA study.

Authors:  Angela Marie Abbatecola; Mario Bo; Mario Barbagallo; Raffaele Antonelli Incalzi; Alberto Pilotto; Giuseppe Bellelli; Stefania Maggi; Giuseppe Paolisso
Journal:  J Am Med Dir Assoc       Date:  2015-02-07       Impact factor: 4.669

2.  Liberating A1C goals in older adults may not protect against the risk of hypoglycemia.

Authors:  Medha N Munshi; Christine Slyne; Alissa R Segal; Nora Saul; Courtney Lyons; Katie Weinger
Journal:  J Diabetes Complications       Date:  2017-03-14       Impact factor: 2.852

3.  Simplification of Insulin Regimen in Older Adults and Risk of Hypoglycemia.

Authors:  Medha N Munshi; Christine Slyne; Alissa R Segal; Nora Saul; Courtney Lyons; Katie Weinger
Journal:  JAMA Intern Med       Date:  2016-07-01       Impact factor: 21.873

Review 4.  Basal insulin treatment in type 2 diabetes.

Authors:  Maka S Hedrington; Lindsay Pulliam; Stephen N Davis
Journal:  Diabetes Technol Ther       Date:  2011-06       Impact factor: 6.118

5.  Diabetes mellitus in older people: position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes.

Authors:  Alan Sinclair; John E Morley; Leo Rodriguez-Mañas; Giuseppe Paolisso; Tony Bayer; Andrej Zeyfang; Isabelle Bourdel-Marchasson; Ulrich Vischer; Jean Woo; Ian Chapman; Trisha Dunning; Graydon Meneilly; Joel Rodriguez-Saldana; Luis Miguel Gutierrez Robledo; Tali Cukierman-Yaffe; Roger Gadsby; Guntram Schernthaner; Kate Lorig
Journal:  J Am Med Dir Assoc       Date:  2012-07       Impact factor: 4.669

6.  Physiological Changes in Older Adults and Their Effect on Diabetes Treatment.

Authors:  Brian J Gates; Kevin M Walker
Journal:  Diabetes Spectr       Date:  2014-02

7.  A Randomized Controlled Trial Comparing Efficacy and Safety of Insulin Glargine 300 Units/mL Versus 100 Units/mL in Older People With Type 2 Diabetes: Results From the SENIOR Study.

Authors:  Robert Ritzel; Stewart B Harris; Helen Baron; Hermes Florez; Ronan Roussel; Melanie Espinasse; Isabel Muehlen-Bartmer; Nianxian Zhang; Monica Bertolini; Claire Brulle-Wohlhueter; Medha Munshi; Geremia B Bolli
Journal:  Diabetes Care       Date:  2018-06-12       Impact factor: 19.112

8.  Elderly patients with diabetes experience a lower rate of nocturnal hypoglycaemia with insulin degludec than with insulin glargine: a meta-analysis of phase IIIa trials.

Authors:  Christopher Sorli; Mark Warren; David Oyer; Henriette Mersebach; Thue Johansen; Stephen C L Gough
Journal:  Drugs Aging       Date:  2013-12       Impact factor: 3.923

9.  Single-dose new insulin glargine 300 U/ml provides prolonged, stable glycaemic control in Japanese and European people with type 1 diabetes.

Authors:  M Shiramoto; T Eto; S Irie; A Fukuzaki; L Teichert; J Tillner; Y Takahashi; M Koyama; R Dahmen; T Heise; R H A Becker
Journal:  Diabetes Obes Metab       Date:  2014-12-22       Impact factor: 6.577

10.  Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes.

Authors:  David M Nathan; John B Buse; Mayer B Davidson; Ele Ferrannini; Rury R Holman; Robert Sherwin; Bernard Zinman
Journal:  Diabetes Care       Date:  2008-10-22       Impact factor: 17.152

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  2 in total

1.  Challenges and Strategies for Managing Diabetes in the Elderly in Long-Term Care Settings.

Authors:  Naushira Pandya; Elizabeth Hames; Sukhman Sandhu
Journal:  Diabetes Spectr       Date:  2020-08

2.  DIVE/DPV registries: benefits and risks of analog insulin use in individuals 75 years and older with type 2 diabetes mellitus.

Authors:  Gesine van Mark; Sascha R Tittel; Reinhard Welp; Jörg Gloyer; Stefan Sziegoleit; Ralf Barion; Peter M Jehle; Dieter Erath; Peter Bramlage; Stefanie Lanzinger
Journal:  BMJ Open Diabetes Res Care       Date:  2021-06
  2 in total

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