Stefano Occhipinti1, Leah Zajdlewicz2, Geoffrey D Coughlin3, John W Yaxley3, Nigel Dunglison3, Robert A Gardiner3,4,5,6, Suzanne K Chambers1,4,6,7. 1. Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia. 2. Cancer Council Queensland, Brisbane, Australia. 3. Department of Urology, Royal Brisbane & Women's Hospital, Brisbane, Australia. 4. The University of Queensland Centre for Clinical Research, Brisbane, Australia. 5. Faculty of Medicine, The University of Queensland, Brisbane, Australia. 6. Edith Cowan University, Perth, Australia. 7. University of Technology Sydney, Sydney, Australia.
Abstract
BACKGROUND: Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care. OBJECTIVE: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post-surgery. MEASUREMENTS: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data. RESULTS AND LIMITATIONS: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men. CONCLUSIONS: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.
BACKGROUND:Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care. OBJECTIVE: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post-surgery. MEASUREMENTS: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data. RESULTS AND LIMITATIONS: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men. CONCLUSIONS: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.
Authors: Erin K Tagai; Suzanne M Miller; Shawna V Hudson; Michael A Diefenbach; Elizabeth Handorf; Alicja Bator; Allison Marziliano; Alexander Kutikov; Simon J Hall; Manish Vira; Michael Schwartz; Issac Yi Kim; Sung Kim Journal: Psychooncology Date: 2021-04-28 Impact factor: 3.955
Authors: Gabriela Ilie; Joshua White; Ross Mason; Ricardo Rendon; Greg Bailly; Joseph Lawen; David Bowes; Nikhilesh Patil; Derek Wilke; Cody MacDonald; Robert Rutledge; David Bell Journal: Am J Mens Health Date: 2020 Sep-Oct
Authors: Jeff Dunn; Anna Green; Nicholas Ralph; Robert U Newton; Andrew Kneebone; Mark Frydenberg; Suzanne K Chambers Journal: BJU Int Date: 2020-08-18 Impact factor: 5.969