Literature DB >> 31659346

Effect of TLRs and nuclear PPARγ receptors on the mechanisms of intestinal carcinogenesis.

Aldona Orzechowska-Jastrząb1, Agata Ptak-Belowska2, Aneta Targosz2.   

Abstract

Tool Like Receptors (TLR) are transmembrane proteins that play an important role in immune reactions associated with the recognition of pathogenic factors that cause infection. However, chronic inflammatory conditions associated with the activation of these receptors create favorable conditions for the development of cancerous processes. The relationship between nuclear PPARγ receptors and TLR receptors is also important, whose role and importance in the process of carcinogenesis is the subject of various studies.

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Keywords:  Tool Like Receptors (TLR); carcinogenesis, cyclooxygenase 2 (COX-2); peroxisome proliferator-activated receptors (PPARs)

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Year:  2019        PMID: 31659346

Source DB:  PubMed          Journal:  Folia Med Cracov        ISSN: 0015-5616


  1 in total

1.  rhEPO Upregulates the PPARγ Pathway in Long-term Cultured Primary Nerve Cells via PI3K/Akt to Delay Cell Senescence.

Authors:  Huqing Wang; Ming Chen; Tao Zhang; Zhen Gao; Yu Gong; Xiaorui Yu; Haiqin Wu
Journal:  J Mol Neurosci       Date:  2022-05-03       Impact factor: 2.866

  1 in total

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