Literature DB >> 31657239

Polymethylmethacrylate patient-matched implants (PMMA-PMI) for complex and revision cranioplasty: analysis of long-term complication rates and patient outcomes.

Henrik Giese1, Jennifer Meyer1, Michael Engel2, Andreas Unterberg1, Christopher Beynon1.   

Abstract

Objective: Cranioplasty (CP) is associated with high complication rates and patient-matched implants (PMI) are frequently used for CP. However, only limited data are available regarding complication rates of PMI-based CP after complex or failed primary CP. Here we report our experience with the use of polymethylmethacrylate (PMMA) PMI for this purpose.Method: We analyzed all patients with complex or failed primary CP and subsequent implantation of PMMA-PMI between 2010 and 2015 at our institution.
Results: A total of 67 patients (29 females, 38 males) with a mean age of 43 years (range: 13-74 years) were included in the study. Primary PMI-CP was performed in 18 patients with destructive or osteolytic bone tumors. Secondary PMI-CP was performed in 49 patients. Complications occurred in 14 patients with an overall complication rate of 21.7% during a mean follow-up of 39.7 ± 23.4 month. Approximately two-thirds of the patients reported a good quality of life after the initial event and subsequent CP. The majority of patients (>90%) was satisfied with the cosmetic result.
Conclusion: Surgical CP with PMMA-PMI appears to be a suitable method for patients with failed or complex CP. Complication rates are comparable to those reported for primary CP.

Entities:  

Keywords:  Cranioplasty; PMMA; decompressive craniectomy; patient matched implant; quality of life

Mesh:

Substances:

Year:  2019        PMID: 31657239     DOI: 10.1080/02699052.2019.1683895

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  1 in total

1.  Outcomes of Cranioplasty Strategies for High-Risk Complex Cranial Defects: A 10-Year Experience.

Authors:  Edgar Soto; Ryan D Restrepo; John H Grant; René P Myers
Journal:  Ann Plast Surg       Date:  2021-10-08       Impact factor: 1.763

  1 in total

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