| Literature DB >> 31655771 |
Shobana Athimulam1, Natalia Lazik2, Irina Bancos3.
Abstract
Low-renin hypertension affects 30% of hypertensive patients. Primary hyperaldosteronism presents with low renin and aldosterone excess. Low-renin, low-aldosterone hypertension represents a wide spectrum of disorders that includes essential low-renin hypertension, hereditary forms of hypertension, and hypertension secondary to endogenous or exogenous factors. This review addresses the different conditions that present with low-renin hypertension, discussing an appropriate diagnostic approach and highlighting the genetic subtypes within familial forms.Entities:
Keywords: Apparent mineralocorticoid excess syndrome; CYP11B1 and CYP17 deficiency; Glucocorticoid-resistance syndrome; Gordon syndrome; Liddle syndrome; Low-renin hypertension; Mineralocorticoid receptor– activating mutation; Primary aldosteronism
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Year: 2019 PMID： 31655771 DOI： 10.1016/j.ecl.2019.08.003
Source DB: PubMed Journal: Endocrinol Metab Clin North Am ISSN： 0889-8529 Impact factor: 4.741