Literature DB >> 3165492

Differentiation of erythroid progenitor (CFU-E) cells from mouse fetal liver cells and murine erythroleukemia (TSA8) cells without proliferation.

T Noguchi1, H Fukumoto, Y Mishina, M Obinata.   

Abstract

Erythropoietin (epo) appears to play a significant role in influencing the proliferation and differentiation of erythroid progenitor (CFU-E) cells. To determine the mechanism of action of epo, the effect of drugs on the in vitro colony formation of CFU-E cells induced from a novel murine erythroleukemia cell line, TSA8, was examined. While cytosine arabinoside inhibited colony formation and terminal differentiation of the CFU-E cells responding to epo, herbimycin, which is a drug that inhibits src-related phosphorylation, inhibited colony formation only. The same effect of herbimycin was observed with normal CFU-E cells from mouse fetal liver cells. These results suggest that epo induces two signals, one for proliferation and the other for differentiation, and that the two signals are not linked in erythroid progenitor cells.

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Year:  1988        PMID： 3165492      PMCID： PMC363462          DOI： 10.1128/mcb.8.6.2604-2609.1988

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  23 in total

1.  Changes in globin messenger RNA content during erythroid cell differentiation.

Authors:  F Ramirez; R Gambino; G M Maniatis; R A Rifkind; P A Marks; A Bank
Journal:  J Biol Chem       Date:  1975-08-10       Impact factor: 5.157

2.  Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis.

Authors:  J Gusella; R Geller; B Clarke; V Weeks; D Housman
Journal:  Cell       Date:  1976-10       Impact factor: 41.582

3.  Murine erythroleukemia cell differentiation: relationship of globin gene expression and of prolongation of G1 to inducer effects during G1/early S.

Authors:  R Gambari; P A Marks; R A Rifkind
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A.

Authors:  N N Iscove; F Sieber; K H Winterhalter
Journal:  J Cell Physiol       Date:  1974-04       Impact factor: 6.384

5.  An extension of the 51Cr-release assay for the estimation of mouse cytotoxins.

Authors:  W Boyle
Journal:  Transplantation       Date:  1968-09       Impact factor: 4.939

Review 6.  Renewal and commitment to differentiation of hemopoietic stem cells (an interpretive review).

Authors:  M Ogawa; P N Porter; T Nakahata
Journal:  Blood       Date:  1983-05       Impact factor: 22.113

Review 7.  Hemopoietic stem cell differentiation.

Authors:  J E Till; E A McCulloch
Journal:  Biochim Biophys Acta       Date:  1980-11-26

8.  Isolation and induction of erythroleukemic cell lines with properties of erythroid progenitor burst-forming cell (BFU-E) and erythroid precursor cell (CFU-E).

Authors:  T Shibuya; T W Mak
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

9.  Erythropoietin effects on fetal mouse erythroid cells. II. Nucleic acid synthesis and the erythropoietin-sensitive cell.

Authors:  M Djaidetti; H Preisler; P A Marks; R A Rifkind
Journal:  J Biol Chem       Date:  1972-02-10       Impact factor: 5.157

10.  Factors controlling induction of commitment of murine erythroleukemia (TSA8) cells to CFU-E (colony forming unit-erythroid).

Authors:  T Noguchi; H Fukumoto; Y Mishina; M Obinata
Journal:  Development       Date:  1987-09       Impact factor: 6.868
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  3 in total

1.  Erythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activation.

Authors:  S Chrétien; P Varlet; F Verdier; S Gobert; J P Cartron; S Gisselbrecht; P Mayeux; C Lacombe
Journal:  EMBO J       Date:  1996-08-15       Impact factor: 11.598

2.  Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells.

Authors:  K Muta; S B Krantz; M C Bondurant; A Wickrema
Journal:  J Clin Invest       Date:  1994-07       Impact factor: 14.808

3.  In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130.

Authors:  A Yoshimura; H F Lodish
Journal:  Mol Cell Biol       Date:  1992-02       Impact factor: 4.272
  3 in total

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