Literature DB >> 31653638

Amiodarone-induced diffuse alveolar haemorrhage: a rare but potentially life-threatening complication of a commonly prescribed medication.

Jamaluddin Saeed1, Qazi Ahmed Waqas2, Uzma Ikhtiar Khan3, Hafez Mohammad Ammar Abdullah4.   

Abstract

Amiodarone is an antiarrhythmic agent that is used commonly in clinical practice. It is associated with many side effects, the most common being pulmonary manifestations. Interstitial pneumonitis is one of the most common complications, however rarely amiodarone can cause diffuse alveolar haemorrhage (DAH) too. We describe the case of a 73-year-old woman who presented with shortness of breath and haemoptysis 4 days after starting amiodarone. She was diagnosed with amiodarone-induced DAH based on imaging and bronchoalveolar lavage. She was treated with intravenous and then oral steroids, and amiodarone was discontinued. The patient made a significant clinical and radiological recovery. She was discharged 10 days after her presentation. This case highlights a rare but potentially life-threatening complication of a commonly used medication. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  arrhythmias; respiratory medicine; unwanted effects/adverse reactions

Mesh:

Substances:

Year:  2019        PMID: 31653638     DOI: 10.1136/bcr-2019-232149

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  2 in total

1.  Endoscopic features and clinical outcomes of cytomegalovirus gastroenterocolitis in immunocompetent patients.

Authors:  Jiyoung Yoon; Junghwan Lee; Dae Sung Kim; Jin Wook Lee; Seung Wook Hong; Ha Won Hwang; Sung Wook Hwang; Sang Hyoung Park; Dong-Hoon Yang; Byong Duk Ye; Seung-Jae Myung; Hwoon-Yong Jung; Suk-Kyun Yang; Jeong-Sik Byeon
Journal:  Sci Rep       Date:  2021-03-18       Impact factor: 4.379

2.  A multicenter retrospective cohort study on predicting the risk for amiodarone pulmonary toxicity.

Authors:  Wang Chun Kwok; Ting Fung Ma; Johnny Wai Man Chan; Herbert H Pang; James Chung Man Ho
Journal:  BMC Pulm Med       Date:  2022-04-05       Impact factor: 3.317

  2 in total

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