Literature DB >> 31650488

Pathological Relationship between Intestinal Flora and Osteoarthritis and Intervention Mechanism of Chinese Medicine.

Yong-Rong Wu1, Gao-Yan Kuang2, Fang-Guo Lu3, Heng-Xin Wang4, Min Lu2, Qing Zhou5.   

Abstract

Chinese medicine (CM) has a good clinical effect on osteoarthritis (OA), but the mechanism is not very clear. Evidence-based medicine researches have shown that intestinal flora plays a role in the pathogenesis and succession of OA. Intestinal flora affects the efficacy of CM, and CM can affect the balance of intestinal flora. This paper focuses on the relationship between intestinal flora, intestinal microenvironment, brain-gut axis, metabolic immunity and OA, and preliminarily expound the significance of intestinal flora in the pathogenesis of OA and the mechanism of CM intervention. The above discussion will be of great significance in the prevention and treatment of OA by CM from the perspective of intestinal flora.

Entities:  

Keywords:  intestinal flora; mechanism of Chinese medicine; osteoarthritis; pathogenesis; treatment

Mesh：

Year:  2019        PMID： 31650488     DOI： 10.1007/s11655-019-3224-2

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN： 1672-0415            Impact factor:   1.978


  40 in total

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Review 2.  Gut microbiota, metabolites and host immunity.

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Review 3.  Osteoarthritis year in review 2016: biology.

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Review 5.  Brain-gut-microbiota axis: challenges for translation in psychiatry.

Authors:  John R Kelly; Gerard Clarke; John F Cryan; Timothy G Dinan
Journal:  Ann Epidemiol       Date:  2016-03-08       Impact factor: 3.797

6.  Analysis of the toll-like receptor 2-2 (TLR2-2) and TLR4 mRNA expression in the intestinal mucosal immunity of broilers fed on diets supplemented with nickel chloride.

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7.  Dysregulated bioenergetics: a key regulator of joint inflammation.

Authors:  M Biniecka; M Canavan; T McGarry; W Gao; J McCormick; S Cregan; L Gallagher; T Smith; J J Phelan; J Ryan; J O'Sullivan; C T Ng; D J Veale; U Fearon
Journal:  Ann Rheum Dis       Date:  2016-03-24       Impact factor: 19.103

Review 8.  Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson's Disease.

Authors:  Valentina Caputi; Maria Cecilia Giron
Journal:  Int J Mol Sci       Date:  2018-06-06       Impact factor: 5.923

9.  Gene expression profiling of the mouse gut: Effect of intestinal flora on intestinal health.

Authors:  Wenhua Zhu; Jun Li; Benyan Wu
Journal:  Mol Med Rep       Date:  2017-12-18       Impact factor: 2.952

10.  Gut to brain interaction in Autism Spectrum Disorders: a randomized controlled trial on the role of probiotics on clinical, biochemical and neurophysiological parameters.

Authors:  Elisa Santocchi; Letizia Guiducci; Francesca Fulceri; Lucia Billeci; Emma Buzzigoli; Fabio Apicella; Sara Calderoni; Enzo Grossi; Maria Aurora Morales; Filippo Muratori
Journal:  BMC Psychiatry       Date:  2016-06-04       Impact factor: 3.630
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  1 in total

Review 1.  Herbal Medicine, Gut Microbiota, and COVID-19.

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