Carlo Lavalle1, Marco V Mariani2, Agostino Piro2, Martina Straito2, Paolo Severino2, Domenico G Della Rocca3, Giovanni B Forleo4, Jorge Romero5, Luigi Di Biase5, Francesco Fedele2. 1. Department of Cardiovascular Disease, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161, Rome, Italy. carlo.lavalle@uniroma1.it. 2. Department of Cardiovascular, Respiratory, Nephrology, Anaesthesiology and Geriatric Sciences, "Sapienza" University of Rome, Rome, Italy. 3. Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA. 4. Department of Cardiology, Luigi Sacco Hospital, Milan, Italy. 5. Department of Cardiology, Montefiore Medical Center, New York, NY, USA.
Abstract
PURPOSE: Idiopathic outflow tract ventricular arrhythmias are ventricular tachycardias or premature ventricular contractions presumably not related to myocardial scar or disorders of ion channels. These arrhythmias have focal origin and display characteristic electrocardiographic features. The purpose of this article is to review the state of the art of diagnosis and treatment of idiopathic outflow tract ventricular arrhythmias. METHODS: We systematically reviewed scientific literature about idiopathic outflow tract ventricular arrhythmias selecting the most relevant papers on this topic. RESULTS: The right ventricle outflow tract is the most common site of origin for outflow tract ventricular arrhythmias, but also left ventricle outflow tract can harbour these arrhythmias. Outflow tract ventricular arrhythmias are generally benign and may require treatment if they are symptomatic, incessant or give rise to cardiomyopathy. Radiofrequency catheter ablation is an effective and safe therapeutic strategy. A successful procedure requires a thorough preoperative analysis of the 12-lead electrocardiogram of the spontaneous arrhythmia combined with a detailed electroanatomical mapping and intracardiac echocardiography. CONCLUSIONS: Idiopathic outflow tract arrhythmias are frequent in daily clinical practice and can be successfully eliminated through discrete radiofrequency catheter ablation with low rates of complications.
PURPOSE: Idiopathic outflow tract ventricular arrhythmias are ventricular tachycardias or premature ventricular contractions presumably not related to myocardial scar or disorders of ion channels. These arrhythmias have focal origin and display characteristic electrocardiographic features. The purpose of this article is to review the state of the art of diagnosis and treatment of idiopathic outflow tract ventricular arrhythmias. METHODS: We systematically reviewed scientific literature about idiopathic outflow tract ventricular arrhythmias selecting the most relevant papers on this topic. RESULTS: The right ventricle outflow tract is the most common site of origin for outflow tract ventricular arrhythmias, but also left ventricle outflow tract can harbour these arrhythmias. Outflow tract ventricular arrhythmias are generally benign and may require treatment if they are symptomatic, incessant or give rise to cardiomyopathy. Radiofrequency catheter ablation is an effective and safe therapeutic strategy. A successful procedure requires a thorough preoperative analysis of the 12-lead electrocardiogram of the spontaneous arrhythmia combined with a detailed electroanatomical mapping and intracardiac echocardiography. CONCLUSIONS: Idiopathic outflow tract arrhythmias are frequent in daily clinical practice and can be successfully eliminated through discrete radiofrequency catheter ablation with low rates of complications.
Authors: Yasuhiro Shirai; Pasquale Santangeli; Jackson J Liang; Fermin C Garcia; Gregory E Supple; David S Frankel; Michael P Riley; David Lin; Robert D Schaller; Sanjay Dixit; David J Callans; Erica S Zado; Francis E Marchlinski Journal: Europace Date: 2019-03-01 Impact factor: 5.214
Authors: Hiroshi Aoyama; Hiroshi Nakagawa; Jan V Pitha; George S Khammar; Krishnaswamy Chandrasekaran; Kagari Matsudaira; Tetsuo Yagi; Katsuaki Yokoyama; Ralph Lazzara; Warren M Jackman Journal: J Cardiovasc Electrophysiol Date: 2005-11
Authors: Shuanglun Xie; Maciej Kubala; Jackson J Liang; Tatsuya Hayashi; Jaeseok Park; Irene Lucena Padros; Fermin C Garcia; Pasquale Santangeli; Gregory E Supple; David S Frankel; Erica S Zado; David Lin; Robert D Schaller; Sanjay Dixit; David J Callans; Saman Nazarian; Francis E Marchlinski Journal: J Cardiovasc Electrophysiol Date: 2018-10-08
Authors: David V Daniels; Yen-Yu Lu; Joseph B Morton; Peter A Santucci; Joseph G Akar; Alex Green; David J Wilber Journal: Circulation Date: 2006-03-27 Impact factor: 29.690
Authors: Can Hasdemir; Safiye Aktas; Figen Govsa; Ekin O Aktas; Aytac Kocak; Yasemin T Bozkaya; Muge I Demirbas; Cem Ulucan; Oner Ozdogan; Meral Kayikcioglu; Levent H Can; Serdar Payzin Journal: Pacing Clin Electrophysiol Date: 2007-04 Impact factor: 1.976
Authors: David Lin; Leonard Ilkhanoff; Edward Gerstenfeld; Sanjay Dixit; Stuart Beldner; Rupa Bala; Fermin Garcia; David Callans; Francis E Marchlinski Journal: Heart Rhythm Date: 2008-02-09 Impact factor: 6.343
Authors: C Pandozi; Marco Valerio Mariani; C Chimenti; V Maestrini; D Filomena; M Magnocavallo; M Straito; A Piro; M Russo; M Galeazzi; S Ficili; F Colivicchi; P Severino; M Mancone; F Fedele; C Lavalle Journal: J Interv Card Electrophysiol Date: 2022-01-24 Impact factor: 1.900
Authors: Marco V Mariani; Agostino Piro; Domenico G Della Rocca; Giovanni B Forleo; Naga Venkata Pothineni; Jorge Romero; Luigi Di Biase; Francesco Fedele; Carlo Lavalle Journal: Arrhythm Electrophysiol Rev Date: 2021-04
Authors: Nicola Tarantino; Domenico G Della Rocca; Nicole S De Leon De La Cruz; Eric D Manheimer; Michele Magnocavallo; Carlo Lavalle; Carola Gianni; Sanghamitra Mohanty; Chintan Trivedi; Amin Al-Ahmad; Rodney P Horton; Mohamed Bassiouny; J David Burkhardt; G Joseph Gallinghouse; Giovanni B Forleo; Luigi Di Biase; Andrea Natale Journal: Medicina (Kaunas) Date: 2021-02-26 Impact factor: 2.430