| Literature DB >> 31647832 |
Alexander Wolff, Michaela Bayerlová, Jochen Gaedcke, Dieter Kube, Tim Beißbarth.
Abstract
[This corrects the article DOI: 10.1371/journal.pone.0197162.].Entities:
Year: 2019 PMID: 31647832 PMCID: PMC6812779 DOI: 10.1371/journal.pone.0224062
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Overview of the proportion of genes and corresponding percentage of differential expressed genes for each pipeline after multiple testing adjustment.
| Pipelines | Consensus DEGs | DEGs unique | ||||||
|---|---|---|---|---|---|---|---|---|
| BL2 | RC | BL2 | RC | |||||
| 58.89% | (169/287) | 67.60% | (48/71) | 19.16% | (55/287) | 12.68% | (9/71) | |
| 49.70% | (169/340) | 52.08% | (50/96) | 29.41% | (100/340) | 29.17% | (28/96) | |
| 45.07% | (169/375) | 34.93% | (51/146) | 41.60% | (156/375) | 53.42% | (78/146) | |
| 45.00% | (9/20) | 16.88% | (26/154) | 55.00% | (11/20) | 79.87% | (123/154) | |
‘Consensus’ stands for the amount of genes shared with at least two other Pipelines and ‘unique’ for genes not found by any other Pipeline from the total amount of genes found by each Pipeline.
Fig 4Significant overlapping genes for the different strategies after multiple test adjustment.
Shown are two Venn diagrams, one for each dataset (BL2 Fig 4A and RC Fig 4B). The different pipelines used here are: TopHat2 and Cufflinks (T&C), STAR and HTSeq-Count (S&HT), Sailfish (Sa), STAR and RSEM (S&R). The microarray data is not included, because there were close to no significant genes after FDR adjustment.