Literature DB >> 31647396

Anti-Alzheimer's Materials Isolated from Marine Bio-resources: A Review.

Anuruddhika Udayangani Rathnayake1, Racheal Abuine1, Yong-Jae Kim1, Hee-Guk Byun1.   

Abstract

The most common type of dementia found in the elderly population is Alzheimer's disease. The disease not only impacts the patients and their families but also the society therefore, the main focus of researchers is to search new bioactive materials for treating AD. The marine environment is a rich source of functional ingredients and to date, we can find sufficient research relating to anti- Alzheimer's compounds isolated from marine environment. Therefore, this review focuses on the anti- Alzheimer's material from marine bio-resources and then expounds on the anti-Alzheimer's compounds from marine seaweed, marine animal and marine microorganisms. Moreover, because of the complexity of the disease, different hypothesizes have been elaborated and active compounds have been isolated to inhibit different stages of pathophysiological mechanisms. Sulfated polysaccharides, glycoprotein, and enzymatic hydrolysates from marine seaweeds, peptides, dietary omega-3 polyunsaturated fatty acids and skeletal polysaccharide from marine animals and secondary metabolites from marine microorganism are summarized in this review under the anti-Alzheimer's compounds from the marine. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Alzheimer's disease; amyloid beta; bioactive compounds; dementia; neurodegeneration; seaweeds; tau protein.

Year:  2019        PMID: 31647396     DOI: 10.2174/1567205016666191024144044

Source DB:  PubMed          Journal:  Curr Alzheimer Res        ISSN: 1567-2050            Impact factor:   3.498


  4 in total

1.  Diagnosis Test Meta-Analysis for Apolipoprotein E in Alzheimer's Disease.

Authors:  Xuan Xiong; Hongtao Xiao; Yuan Zhang; Dongke Yu; Junlan Chuan; Lei Zhong; Qinan Yin; Rongsheng Tong
Journal:  Dis Markers       Date:  2020-10-09       Impact factor: 3.434

Review 2.  Neuroprotective effects of naturally sourced bioactive polysaccharides: an update.

Authors:  Xiao-Lan Xu; Song Li; Rong Zhang; Wei-Dong Le
Journal:  Neural Regen Res       Date:  2022-09       Impact factor: 5.135

Review 3.  A Critical Review of the Abilities, Determinants, and Possible Molecular Mechanisms of Seaweed Polysaccharides Antioxidants.

Authors:  Zhiwei Liu; Xian Sun
Journal:  Int J Mol Sci       Date:  2020-10-21       Impact factor: 5.923

Review 4.  Prospects of Marine Sterols against Pathobiology of Alzheimer's Disease: Pharmacological Insights and Technological Advances.

Authors:  Md Ataur Rahman; Raju Dash; Abdullah Al Mamun Sohag; Mahboob Alam; Hyewhon Rhim; Hunjoo Ha; Il Soo Moon; Md Jamal Uddin; Md Abdul Hannan
Journal:  Mar Drugs       Date:  2021-03-20       Impact factor: 5.118

  4 in total

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