Gerhard Sulo1,2, Jannicke Igland3, Simon Øverland1,4, Grace M Egeland3,5, Gregory A Roth6, Stein E Vollset6, Grethe S Tell3,7. 1. Centre for Disease Burden, Division of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway. 2. Oral Health Centre of Expertise in Western Norway, Bergen, Norway. 3. Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. 4. Department of Psychosocial Science, University of Bergen, Bergen, Norway. 5. Divisions of Health Data and Digitalization and Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway. 6. Institute for Health Metrics and Evaluation (IHME), University of Washington, Seattle, WA, USA. 7. Division of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway.
Abstract
AIMS: To examine trends in heart failure (HF) hospitalization rates and risk of readmissions following an incident HF hospitalization. METHODS AND RESULTS: During 2000-2014, we identified in the Cardiovascular Disease in Norway Project 142 109 hospitalizations with HF as primary diagnosis. Trends of incident and total (incident and recurrent) HF hospitalization rates were analysed using negative binomial regression models. Changes over time in 30-day and 3-year risk of HF recurrences or cardiovascular disease (CVD)-related readmissions were analysed using Fine and Grey competing risk regression, with death as competing events. Age-standardized rates declined on average 1.9% per year in men and 1.8% per year in women for incident HF hospitalizations (both Ptrend < 0.001) but did not change significantly in either men or women for total HF hospitalizations. In men surviving the incident HF hospitalization, 30-day and 3-year risk of a HF recurrent event increased 1.7% and 1.2% per year, respectively. Similarly, 30-day and 3-year risk of a CVD-related hospitalization increased 1.5% and 1.0% per year, respectively (all Ptrend < 0.001). No statistically significant changes in the risk of HF recurrences or CVD-related readmissions were observed among women. In-hospital mortality for a first and recurrent HF episode declined over time in both men and women. CONCLUSIONS: Incident HF hospitalization rates declined in Norway during 2000-2014. An increase in the risk of recurrences in the context of reduced in-hospital mortality following an incident and recurrent HF hospitalization led to flat trends of total HF hospitalization rates.
AIMS: To examine trends in heart failure (HF) hospitalization rates and risk of readmissions following an incident HF hospitalization. METHODS AND RESULTS: During 2000-2014, we identified in the Cardiovascular Disease in Norway Project 142 109 hospitalizations with HF as primary diagnosis. Trends of incident and total (incident and recurrent) HF hospitalization rates were analysed using negative binomial regression models. Changes over time in 30-day and 3-year risk of HF recurrences or cardiovascular disease (CVD)-related readmissions were analysed using Fine and Grey competing risk regression, with death as competing events. Age-standardized rates declined on average 1.9% per year in men and 1.8% per year in women for incident HF hospitalizations (both Ptrend < 0.001) but did not change significantly in either men or women for total HF hospitalizations. In men surviving the incident HF hospitalization, 30-day and 3-year risk of a HF recurrent event increased 1.7% and 1.2% per year, respectively. Similarly, 30-day and 3-year risk of a CVD-related hospitalization increased 1.5% and 1.0% per year, respectively (all Ptrend < 0.001). No statistically significant changes in the risk of HF recurrences or CVD-related readmissions were observed among women. In-hospital mortality for a first and recurrent HF episode declined over time in both men and women. CONCLUSIONS: Incident HF hospitalization rates declined in Norway during 2000-2014. An increase in the risk of recurrences in the context of reduced in-hospital mortality following an incident and recurrent HF hospitalization led to flat trends of total HF hospitalization rates.
Authors: Willemien J Kruik-Kollöffel; Job van der Palen; Carine J M Doggen; Marissa C van Maaren; H Joost Kruik; Edith M Heintjes; Kris L L Movig; Gerard C M Linssen Journal: PLoS One Date: 2020-12-22 Impact factor: 3.240
Authors: Luis E Rohde; Conrado R Hoffmann Filho; Marciane M Rover; Eneida Rejane Rabelo-Silva; Letícia Lopez; Luiz C S Passos; Odilson M Silvestre; Silvia M Martins; José A de Figueiredo Neto; Fábio S Silveira; Manoel F Canesin; Marcus V Simões; Fábio Akio Nishijuka; Eduardo G Bertoldi; Luiz C Danzmann; Ricardo Mourilhe-Rocha; Ellen Hettwer Magedanz; Mauro Esteves; Fábio M de Castilho; Miguel M Fernandes-Silva; Luiz E F Ritt; Mariana Blacher; Rafael M Soares; Alexandre B Cavalcanti; Felix Ramirez Journal: ESC Heart Fail Date: 2021-09-18